Literature DB >> 19380225

Rapid identification of improved protein ligands using peptoid microarrays.

Hyun-Suk Lim1, M Muralidhar Reddy, Xiangshu Xiao, Johnnie Wilson, Rosemary Wilson, Steven Connell, Thomas Kodadek.   

Abstract

A rapid array-based protocol is presented by which a modest affinity protein-binding small molecule can be appended to a library of peptoids via click chemistry. The array can then be screened for improved ligands that exhibit a higher affinity for the protein target.

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Year:  2009        PMID： 19380225      PMCID： PMC4452005          DOI： 10.1016/j.bmcl.2009.03.153

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  18 in total

1.  Combinatorial target-guided ligand assembly: identification of potent subtype-selective c-Src inhibitors.

Authors:  D J Maly; I C Choong; J A Ellman
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

2.  Transformation of low-affinity lead compounds into high-affinity protein capture agents.

Authors:  M Muralidhar Reddy; Kiran Bachhawat-Sikder; Thomas Kodadek
Journal:  Chem Biol       Date:  2004-08

3.  Isolation of protein ligands from large peptoid libraries.

Authors:  Prasanna G Alluri; M Muralidhar Reddy; Kiran Bachhawat-Sikder; Hernando J Olivos; Thomas Kodadek
Journal:  J Am Chem Soc       Date:  2003-11-19       Impact factor: 15.419

Review 4.  Signaling protein inhibitors via the combinatorial modification of peptide scaffolds.

Authors:  David S Lawrence
Journal:  Biochim Biophys Acta       Date:  2005-09-12

5.  Protein "fingerprinting" in complex mixtures with peptoid microarrays.

Authors:  M Muralidhar Reddy; Thomas Kodadek
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-25       Impact factor: 11.205

6.  A cell-permeable synthetic transcription factor mimic.

Authors:  Xiangshu Xiao; Peng Yu; Hyun-Suk Lim; Devanjan Sikder; Thomas Kodadek
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

7.  A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity.

Authors:  D Cussac; M Vidal; C Leprince; W Q Liu; F Cornille; G Tiraboschi; B P Roques; C Garbay
Journal:  FASEB J       Date:  1999-01       Impact factor: 5.191

8.  Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants.

Authors:  Pi-Hui Liang; Sheng-Kai Wang; Chi-Huey Wong
Journal:  J Am Chem Soc       Date:  2007-08-18       Impact factor: 15.419

9.  Design and synthesis of a cell-permeable synthetic transcription factor mimic.

Authors:  Xiangshu Xiao; Peng Yu; Hyun-Suk Lim; Devanjan Sikder; Thomas Kodadek
Journal:  J Comb Chem       Date:  2007-05-27

10.  Conjugates of catecholamines. 1. N-alkyl-functionalized carboxylic acid congeners and amides related to isoproterenol.

Authors:  K A Jacobson; D Marr-Leisy; R P Rosenkranz; M S Verlander; K L Melmon; M Goodman
Journal:  J Med Chem       Date:  1983-04       Impact factor: 7.446
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  9 in total

1.  Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library.

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Journal:  Bioorg Med Chem       Date:  2016-04-23       Impact factor: 3.641

Review 2.  Synthetic receptors with antibody-like binding affinities.

Authors:  Thomas Kodadek
Journal:  Curr Opin Chem Biol       Date:  2010-07-30       Impact factor: 8.822

3.  Development of homomultimers and heteromultimers of lung cancer-specific peptoids.

Authors:  Jared C Hooks; Jaya P Matharage; D Gomika Udugamasooriya
Journal:  Biopolymers       Date:  2011       Impact factor: 2.505

4.  Aβ42-binding peptoids as amyloid aggregation inhibitors and detection ligands.

Authors:  Yuan Luo; Sheetal Vali; Suya Sun; Xuesong Chen; Xia Liang; Tatiana Drozhzhina; Elena Popugaeva; Ilya Bezprozvanny
Journal:  ACS Chem Neurosci       Date:  2013-03-07       Impact factor: 4.418

5.  The Privileged Chemical Space Predictor (PCSP): a computer program that identifies privileged chemical space from screens of modularly assembled chemical libraries.

Authors:  Steven J Seedhouse; Lucas P Labuda; Matthew D Disney
Journal:  Bioorg Med Chem Lett       Date:  2010-01-11       Impact factor: 2.823

6.  An efficient strategy to enhance binding affinity and specificity of a known isozyme inhibitor.

Authors:  Joo-Eun Jee; Jaehong Lim; Yong Siang Ong; Jessica Oon; Liqian Gao; Hak Soo Choi; Su Seong Lee
Journal:  Org Biomol Chem       Date:  2016-07-12       Impact factor: 3.876

7.  A General Method to Discover Epitopes from Sera.

Authors:  Kurt Whittemore; Stephen Albert Johnston; Kathryn Sykes; Luhui Shen
Journal:  PLoS One       Date:  2016-06-14       Impact factor: 3.240

Review 8.  Solid-phase synthesis of N-substituted glycine oligomers (alpha-peptoids) and derivatives.

Authors:  Adrian S Culf; Rodney J Ouellette
Journal:  Molecules       Date:  2010-08-04       Impact factor: 4.411

9.  Evaluation of phage display discovered peptides as ligands for prostate-specific membrane antigen (PSMA).

Authors:  Duanwen Shen; Fei Xie; W Barry Edwards
Journal:  PLoS One       Date:  2013-07-25       Impact factor: 3.240
  9 in total

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