Literature DB >> 19380208

Numb--from flies to humans.

Benedict Yan1.   

Abstract

Numb carries the distinction of being the first molecule discovered to influence cell fate by being asymmetrically segregated during cell division. Originally identified from studies in Drosophila, further work has since demonstrated the importance of Numb in mammalian and, in particular, human systems, from diverse fields such as developmental neurobiology to cancer biology and neurodegenerative disease. This review surveys the body of knowledge concerning Numb, and discusses the relevance of Numb to human biology and disease. Copyright (c) 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID： 19380208     DOI： 10.1016/j.braindev.2009.03.008

Source DB:  PubMed          Journal:  Brain Dev        ISSN： 0387-7604            Impact factor:   1.961


  9 in total

1.  Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.

Authors:  Ximing Shao; Zhihao Ding; Ming Zhao; Ke Liu; Haiyan Sun; Juntao Chen; Xianming Liu; Yuzhen Zhang; Yang Hong; Huashun Li; Hongchang Li
Journal:  J Biol Chem       Date:  2017-10-17       Impact factor: 5.157

Review 2.  How signaling between cells can orient a mitotic spindle.

Authors:  Adam D Werts; Bob Goldstein
Journal:  Semin Cell Dev Biol       Date:  2011-07-23       Impact factor: 7.727

3.  Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma.

Authors:  Yinying Lu; Wanping Xu; Junfang Ji; Dechun Feng; Carole Sourbier; Youfeng Yang; Jianhui Qu; Zhen Zeng; Chunping Wang; Xiujuan Chang; Yan Chen; Alok Mishra; Max Xu; Min-Jung Lee; Sunmin Lee; Jane Trepel; W Marston Linehan; Xinwei Wang; Yongping Yang; Len Neckers
Journal:  Hepatology       Date:  2015-07-03       Impact factor: 17.425

4.  ATP11A promotes EMT by regulating Numb PRRL in pancreatic cancer cells.

Authors:  Lin Chen; Jingtong Tang; Weiwei Sheng; Jian Sun; Yuteng Ma; Ming Dong
Journal:  PeerJ       Date:  2022-03-23       Impact factor: 2.984

5.  Numb is required for optimal contraction of skeletal muscle.

Authors:  Rita De Gasperi; Chenglin Mo; Daniella Azulai; Zhiying Wang; Lauren M Harlow; Yating Du; Zachary Graham; Jiangping Pan; Xin-Hua Liu; Lei Guo; Bin Zhang; Fred Ko; Ashleigh M Raczkowski; William A Bauman; Chris N Goulbourne; Wei Zhao; Marco Brotto; Christopher P Cardozo
Journal:  J Cachexia Sarcopenia Muscle       Date:  2022-01-09       Impact factor: 12.910

Review 6.  Aberrant regulation of FBW7 in cancer.

Authors:  Lixia Wang; Xiantao Ye; Yueyong Liu; Wenyi Wei; Zhiwei Wang
Journal:  Oncotarget       Date:  2014-04-30

7.  RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.

Authors:  Woan-Yuh Tarn; Hung-Che Kuo; Hsin-I Yu; Shin-Wu Liu; Ching-Tzu Tseng; Dodda Dhananjaya; Kuan-Yang Hung; Chi-Chiang Tu; Shuo-Hsiu Chang; Guo-Jen Huang; Ing-Ming Chiu
Journal:  Mol Biol Cell       Date:  2016-03-23       Impact factor: 4.138

Review 8.  Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT.

Authors:  Ernestina M De Francesco; Marcello Maggiolini; Anna Maria Musti
Journal:  Int J Mol Sci       Date:  2018-07-10       Impact factor: 5.923

9.  A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells.

Authors:  Yapu Li; Ding Wang; Hongtao Wang; Xin Huang; Yuqi Wen; BingRui Wang; Changlu Xu; Jie Gao; Jinhua Liu; Jingyuan Tong; Mengge Wang; Pei Su; Sirui Ren; Feng Ma; Hong-Dong Li; Emery H Bresnick; Jiaxi Zhou; Lihong Shi
Journal:  EMBO Rep       Date:  2020-12-15       Impact factor: 9.071
  9 in total

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