Literature DB >> 19380109

The tangled web of signaling in innate immunity.

Jeffrey J Coleman1, Eleftherios Mylonakis.   

Abstract

Similarities in innate immune signaling exist between mammals and the nematode Caenorhabditis elegans. Now, Ziegler et al. (2009) and Ren et al. (2009) demonstrate that a protein kinase C delta homolog in C. elegans is involved in innate immunity, providing evidence that the conservation of immune signaling networks extends further than previously thought.

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Year:  2009        PMID: 19380109      PMCID: PMC3736815          DOI: 10.1016/j.chom.2009.04.002

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  12 in total

1.  A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.

Authors:  Dennis H Kim; Rhonda Feinbaum; Geneviève Alloing; Fred E Emerson; Danielle A Garsin; Hideki Inoue; Miho Tanaka-Hino; Naoki Hisamoto; Kunihiro Matsumoto; Man-Wah Tan; Frederick M Ausubel
Journal:  Science       Date:  2002-07-26       Impact factor: 47.728

Review 2.  Worms and flies as genetically tractable animal models to study host-pathogen interactions.

Authors:  Eleftherios Mylonakis; Alejandro Aballay
Journal:  Infect Immun       Date:  2005-07       Impact factor: 3.441

3.  Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR.

Authors:  Katie L Styer; Varsha Singh; Evan Macosko; Sarah E Steele; Cornelia I Bargmann; Alejandro Aballay
Journal:  Science       Date:  2008-09-18       Impact factor: 47.728

Review 4.  Distinctive activation mechanisms and functions for protein kinase Cdelta.

Authors:  Susan F Steinberg
Journal:  Biochem J       Date:  2004-12-15       Impact factor: 3.857

5.  Protein kinase Cdelta binds TIRAP/Mal to participate in TLR signaling.

Authors:  Miho Kubo-Murai; Kaoru Hazeki; Naoe Sukenobu; Kyoko Yoshikawa; Kiyomi Nigorikawa; Kazumi Inoue; Toshiyoshi Yamamoto; Misako Matsumoto; Tsukasa Seya; Norimitsu Inoue; Osamu Hazeki
Journal:  Mol Immunol       Date:  2006-12-11       Impact factor: 4.407

6.  Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade.

Authors:  Katja Ziegler; C Léopold Kurz; Sophie Cypowyj; Carole Couillault; Matthieu Pophillat; Nathalie Pujol; Jonathan J Ewbank
Journal:  Cell Host Microbe       Date:  2009-04-23       Impact factor: 21.023

7.  A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans.

Authors:  Kirthi C Reddy; Erik C Andersen; Leonid Kruglyak; Dennis H Kim
Journal:  Science       Date:  2009-01-16       Impact factor: 47.728

8.  TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

Authors:  Carole Couillault; Nathalie Pujol; Jérôme Reboul; Laurence Sabatier; Jean-François Guichou; Yuji Kohara; Jonathan J Ewbank
Journal:  Nat Immunol       Date:  2004-03-28       Impact factor: 25.606

9.  The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response.

Authors:  Jennifer R Powell; Dennis H Kim; Frederick M Ausubel
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-05       Impact factor: 11.205

10.  Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection.

Authors:  Daniel Wong; Daphne Bazopoulou; Nathalie Pujol; Nektarios Tavernarakis; Jonathan J Ewbank
Journal:  Genome Biol       Date:  2007       Impact factor: 13.583

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  4 in total

1.  Using C. elegans for antimicrobial drug discovery.

Authors:  Athanasios Desalermos; Maged Muhammed; Justin Glavis-Bloom; Eleftherios Mylonakis
Journal:  Expert Opin Drug Discov       Date:  2011-06-01       Impact factor: 6.098

2.  A UPR-independent infection-specific role for a BiP/GRP78 protein in the control of antimicrobial peptide expression in C. elegans epidermis.

Authors:  Carole Couillault; Patrick Fourquet; Matthieu Pophillat; Jonathan J Ewbank
Journal:  Virulence       Date:  2012-05-01       Impact factor: 5.882

3.  The pseudokinase NIPI-4 is a novel regulator of antimicrobial peptide gene expression.

Authors:  Sid Ahmed Labed; Shizue Omi; Martha Gut; Jonathan J Ewbank; Nathalie Pujol
Journal:  PLoS One       Date:  2012-03-21       Impact factor: 3.240

4.  The Caenorhabditis elegans p38 MAPK Gene plays a key role in protection from mycobacteria.

Authors:  Thushara Galbadage; Tonya F Shepherd; Suat L G Cirillo; Tina L Gumienny; Jeffrey D Cirillo
Journal:  Microbiologyopen       Date:  2016-02-25       Impact factor: 3.139

  4 in total

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