| Literature DB >> 19378990 |
Josef Scheiber1, Jeremy L Jenkins, Sai Chetan K Sukuru, Andreas Bender, Dmitri Mikhailov, Mariusz Milik, Kamal Azzaoui, Steven Whitebread, Jacques Hamon, Laszlo Urban, Meir Glick, John W Davies.
Abstract
We present a novel method to better investigate adverse drug reactions in chemical space. By integrating data sources about adverse drug reactions of drugs with an established cheminformatics modeling method, we generate a data set that is then visualized with a systems biology tool. Thereby new insights into undesired drug effects are gained. In this work, we present a global analysis linking chemical features to adverse drug reactions.Mesh：
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Year: 2009 PMID： 19378990 DOI： 10.1021/jm801546k
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446