Literature DB >> 19378584

Standardization of anesthesia in swine for experimental cardiovascular surgeries.

Glaucylara Reis Geovanini1, Fábio R Pinna, Flávio A P Prado, Wagner Tetsuji Tamaki, Euclides Marques.   

Abstract

BACKGROUND AND OBJECTIVES: Although dogs are the animals used more often in Experimental Surgeries, the use of sheep, bovine, and swine as models for scientific experiments has been growing. Thus, further learning on the treatment and basic standardization of more complex surgeries in swine are necessary. The objective of this study was to evaluate sedation and analgesia, obtained by the intramuscular administration of midazolam and ketamine, and local anesthetics with 2% lidocaine without vasoconstrictor, in tracheostomy and dissection of femoral artery and vein.
METHODS: The heart rate and corneal-palpebral reflex were evaluated at the beginning of sedation, during the surgical procedures, and at the end of those procedures. Eight Large White swine, without prior treatment, weighing 35 to 42 kg were provided by local farms. They received intramuscular injections of 22 mg.kg of ketamine and 0.3 mg.kg(-1) of midazolam.
RESULTS: The anesthetic approach on those animals, who present both difficult intubation and access to deep vessels, proved to be safe for sedation and analgesia by the method chosen: intramuscular administration.
CONCLUSIONS: An adequate plane of anesthesia for the proposed procedure was achieved.

Entities:  

Mesh:

Year:  2008        PMID: 19378584     DOI: 10.1590/s0034-70942008000400005

Source DB:  PubMed          Journal:  Rev Bras Anestesiol        ISSN: 0034-7094            Impact factor:   0.964


  5 in total

Review 1.  Anesthesia Protocols used to Create Ischemia Reperfusion Myocardial Infarcts in Swine.

Authors:  Ana Abad Cobo; Francisco M Sánchez Margallo; Claudia Báez Díaz; Virginia Blanco Blázquez; Irene González Bueno; Verónica Crisóstomo
Journal:  J Am Assoc Lab Anim Sci       Date:  2020-07-24       Impact factor: 1.232

2.  Correlation of Sedline-generated variables and clinical signs with anaesthetic depth in experimental pigs receiving propofol.

Authors:  Alessandro Mirra; Claudia Spadavecchia; Olivier Levionnois
Journal:  PLoS One       Date:  2022-09-29       Impact factor: 3.752

3.  Physiological and Clinical Responses in Pigs in Relation to Plasma Concentrations during Anesthesia with Dexmedetomidine, Tiletamine, Zolazepam, and Butorphanol.

Authors:  Anneli Rydén; Marianne Jensen-Waern; Görel Nyman; Lena Olsén
Journal:  Animals (Basel)       Date:  2021-05-21       Impact factor: 2.752

4.  Novel and effective balanced intravenous-inhalant anaesthetic protocol in swine by using unrestricted drugs.

Authors:  Luigino Calzetta; Piero Rossi; Pierluigi Bove; Pietro Alfonsi; Luigi Bonizzi; Paola Roncada; Roberta Bernardini; Edoardo Ricciardi; Mauro Montuori; Elena Pistocchini; Paolo Mauti; Maurizio Mattei
Journal:  Exp Anim       Date:  2014-07-15

5.  The use of a plastic guide improves the safety and reduces the duration of endotracheal intubation in the pig.

Authors:  Adrian Janiszewski; Robert Pasławski; Piotr Skrzypczak; Urszula Pasławska; Andrzej Szuba; Józef Nicpoń
Journal:  J Vet Med Sci       Date:  2014-06-16       Impact factor: 1.267

  5 in total

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