Literature DB >> 19378293

Target-based drug discovery: the emerging success of frontal affinity chromatography coupled to mass spectrometry.

Enrica Calleri1, Caterina Temporini, Gabriele Caccialanza, Gabriella Massolini.   

Abstract

Frontal affinity chromatography coupled to mass spectrometry (FAC-MS) has been reported as a potential method for screening compound mixtures against immobilized target proteins. The potentiality of this analytical approach is described and illustrated with a number of examples based on targets of pharmaceutical interest.

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Year:  2009        PMID： 19378293     DOI： 10.1002/cmdc.200800436

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


  8 in total

Review 1.  The development and characterization of protein-based stationary phases for studying drug-protein and protein-protein interactions.

Authors:  Mitesh Sanghvi; Ruin Moaddel; Irving W Wainer
Journal:  J Chromatogr A       Date:  2011-05-27       Impact factor: 4.759

2.  Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor.

Authors:  Enrica Calleri; Stefania Ceruti; Gloria Cristalli; Claudia Martini; Caterina Temporini; Chiara Parravicini; Rosaria Volpini; Simona Daniele; Gabriele Caccialanza; Davide Lecca; Catia Lambertucci; Maria Letizia Trincavelli; Gabriella Marucci; Irving W Wainer; Graziella Ranghino; Piercarlo Fantucci; Maria P Abbracchio; Gabriella Massolini
Journal:  J Med Chem       Date:  2010-05-13       Impact factor: 7.446

Review 3.  Targeting Anti-Cancer Active Compounds: Affinity-Based Chromatographic Assays.

Authors:  Marcela Cristina de Moraes; Carmen Lucia Cardoso; Cláudia Seidl; Ruin Moaddel; Quezia Bezerra Cass
Journal:  Curr Pharm Des       Date:  2016       Impact factor: 3.116

Review 4.  Analysis of biomolecular interactions using affinity microcolumns: a review.

Authors:  Xiwei Zheng; Zhao Li; Sandya Beeram; Maria Podariu; Ryan Matsuda; Erika L Pfaunmiller; Christopher J White; NaTasha Carter; David S Hage
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2014-01-27       Impact factor: 3.205

5.  Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection.

Authors:  C Temporini; G Pochetti; G Fracchiolla; L Piemontese; R Montanari; R Moaddel; A Laghezza; F Altieri; L Cervoni; D Ubiali; E Prada; F Loiodice; G Massolini; E Calleri
Journal:  J Chromatogr A       Date:  2013-02-16       Impact factor: 4.759

Review 6.  Recent developments in protein-ligand affinity mass spectrometry.

Authors:  Niels Jonker; Jeroen Kool; Hubertus Irth; Wilfried M A Niessen
Journal:  Anal Bioanal Chem       Date:  2010-11-08       Impact factor: 4.142

7.  Synthesis and Ability of New Ligands for G Protein-Coupled Receptors 17 (GPR17).

Authors:  Tongyou Zhuo; Shengxue Zhou; Wei Zhang; Catia Lambertucci; Rosaria Volpini
Journal:  Med Sci Monit       Date:  2017-02-22

Review 8.  Solid-Supported Proteins in the Liquid Chromatography Domain to Probe Ligand-Target Interactions.

Authors:  Marcela Cristina de Moraes; Carmen Lucia Cardoso; Quezia Bezerra Cass
Journal:  Front Chem       Date:  2019-11-15       Impact factor: 5.221
  8 in total

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