| Literature DB >> 19378153 |
Abstract
The analysis of DNA sequence polymorphisms and SNPs (single nucleotide polymorphisms) can provide insights into the evolutionary forces acting on populations and species. Available population-genetic methods, and particularly those based on the coalescent theory, have become the primary framework to analyze such DNA polymorphism data. Here, I explain some essential analytical methods for interpreting DNA polymorphism data and also describe the basic functionalities of the DnaSP software. DnaSP is a multi-propose program that allows conducting exhaustive DNA polymorphism analysis using a graphical user-friendly interface.Mesh:
Year: 2009 PMID: 19378153 DOI: 10.1007/978-1-59745-251-9_17
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745