Literature DB >> 19378149

Promoter analysis: gene regulatory motif identification with A-GLAM.

Leonardo Mariño-Ramírez1, Kannan Tharakaraman, John L Spouge, David Landsman.   

Abstract

Reliable detection of cis-regulatory elements in promoter regions is a difficult and unsolved problem in computational biology. The intricacy of transcriptional regulation in higher eukaryotes, primarily in metazoans, could be a major driving force of organismal complexity. Eukaryotic genome annotations have improved greatly due to large-scale characterization of full-length cDNAs, transcriptional start sites (TSSs), and comparative genomics. Regulatory elements are identified in promoter regions using a variety of enumerative or alignment-based methods. Here we present a survey of recent computational methods for eukaryotic promoter analysis and describe the use of an alignment-based method implemented in the A-GLAM program.

Entities:  

Mesh：

Year:  2009        PMID： 19378149      PMCID： PMC2702474          DOI： 10.1007/978-1-59745-251-9_13

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  43 in total

1.  Genome-wide location and function of DNA binding proteins.

Authors:  B Ren; F Robert; J J Wyrick; O Aparicio; E G Jennings; I Simon; J Zeitlinger; J Schreiber; N Hannett; E Kanin; T L Volkert; C J Wilson; S P Bell; R A Young
Journal:  Science       Date:  2000-12-22       Impact factor: 47.728

2.  Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae.

Authors:  J D Hughes; P W Estep; S Tavazoie; G M Church
Journal:  J Mol Biol       Date:  2000-03-10       Impact factor: 5.469

3.  Identification and analysis of eukaryotic promoters: recent computational approaches.

Authors:  U Ohler; H Niemann
Journal:  Trends Genet       Date:  2001-02       Impact factor: 11.639

4.  Initial sequencing and analysis of the human genome.

Authors:  E S Lander; L M Linton; B Birren; C Nusbaum; M C Zody; J Baldwin; K Devon; K Dewar; M Doyle; W FitzHugh; R Funke; D Gage; K Harris; A Heaford; J Howland; L Kann; J Lehoczky; R LeVine; P McEwan; K McKernan; J Meldrim; J P Mesirov; C Miranda; W Morris; J Naylor; C Raymond; M Rosetti; R Santos; A Sheridan; C Sougnez; Y Stange-Thomann; N Stojanovic; A Subramanian; D Wyman; J Rogers; J Sulston; R Ainscough; S Beck; D Bentley; J Burton; C Clee; N Carter; A Coulson; R Deadman; P Deloukas; A Dunham; I Dunham; R Durbin; L French; D Grafham; S Gregory; T Hubbard; S Humphray; A Hunt; M Jones; C Lloyd; A McMurray; L Matthews; S Mercer; S Milne; J C Mullikin; A Mungall; R Plumb; M Ross; R Shownkeen; S Sims; R H Waterston; R K Wilson; L W Hillier; J D McPherson; M A Marra; E R Mardis; L A Fulton; A T Chinwalla; K H Pepin; W R Gish; S L Chissoe; M C Wendl; K D Delehaunty; T L Miner; A Delehaunty; J B Kramer; L L Cook; R S Fulton; D L Johnson; P J Minx; S W Clifton; T Hawkins; E Branscomb; P Predki; P Richardson; S Wenning; T Slezak; N Doggett; J F Cheng; A Olsen; S Lucas; C Elkin; E Uberbacher; M Frazier; R A Gibbs; D M Muzny; S E Scherer; J B Bouck; E J Sodergren; K C Worley; C M Rives; J H Gorrell; M L Metzker; S L Naylor; R S Kucherlapati; D L Nelson; G M Weinstock; Y Sakaki; A Fujiyama; M Hattori; T Yada; A Toyoda; T Itoh; C Kawagoe; H Watanabe; Y Totoki; T Taylor; J Weissenbach; R Heilig; W Saurin; F Artiguenave; P Brottier; T Bruls; E Pelletier; C Robert; P Wincker; D R Smith; L Doucette-Stamm; M Rubenfield; K Weinstock; H M Lee; J Dubois; A Rosenthal; M Platzer; G Nyakatura; S Taudien; A Rump; H Yang; J Yu; J Wang; G Huang; J Gu; L Hood; L Rowen; A Madan; S Qin; R W Davis; N A Federspiel; A P Abola; M J Proctor; R M Myers; J Schmutz; M Dickson; J Grimwood; D R Cox; M V Olson; R Kaul; C Raymond; N Shimizu; K Kawasaki; S Minoshima; G A Evans; M Athanasiou; R Schultz; B A Roe; F Chen; H Pan; J Ramser; H Lehrach; R Reinhardt; W R McCombie; M de la Bastide; N Dedhia; H Blöcker; K Hornischer; G Nordsiek; R Agarwala; L Aravind; J A Bailey; A Bateman; S Batzoglou; E Birney; P Bork; D G Brown; C B Burge; L Cerutti; H C Chen; D Church; M Clamp; R R Copley; T Doerks; S R Eddy; E E Eichler; T S Furey; J Galagan; J G Gilbert; C Harmon; Y Hayashizaki; D Haussler; H Hermjakob; K Hokamp; W Jang; L S Johnson; T A Jones; S Kasif; A Kaspryzk; S Kennedy; W J Kent; P Kitts; E V Koonin; I Korf; D Kulp; D Lancet; T M Lowe; A McLysaght; T Mikkelsen; J V Moran; N Mulder; V J Pollara; C P Ponting; G Schuler; J Schultz; G Slater; A F Smit; E Stupka; J Szustakowki; D Thierry-Mieg; J Thierry-Mieg; L Wagner; J Wallis; R Wheeler; A Williams; Y I Wolf; K H Wolfe; S P Yang; R F Yeh; F Collins; M S Guyer; J Peterson; A Felsenfeld; K A Wetterstrand; A Patrinos; M J Morgan; P de Jong; J J Catanese; K Osoegawa; H Shizuya; S Choi; Y J Chen; J Szustakowki
Journal:  Nature       Date:  2001-02-15       Impact factor: 49.962

5.  ANN-Spec: a method for discovering transcription factor binding sites with improved specificity.

Authors:  C T Workman; G D Stormo
Journal:  Pac Symp Biocomput       Date:  2000

6.  A higher-order background model improves the detection of promoter regulatory elements by Gibbs sampling.

Authors:  G Thijs; M Lescot; K Marchal; S Rombauts; B De Moor; P Rouzé; Y Moreau
Journal:  Bioinformatics       Date:  2001-12       Impact factor: 6.937

7.  Finding composite regulatory patterns in DNA sequences.

Authors:  Eleazar Eskin; Pavel A Pevzner
Journal:  Bioinformatics       Date:  2002       Impact factor: 6.937

8.  YMF: A program for discovery of novel transcription factor binding sites by statistical overrepresentation.

Authors:  Saurabh Sinha; Martin Tompa
Journal:  Nucleic Acids Res       Date:  2003-07-01       Impact factor: 16.971

9.  Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

Authors:  Piero Carninci; Kazunori Waki; Toshiyuki Shiraki; Hideaki Konno; Kazuhiro Shibata; Masayoshi Itoh; Katsunori Aizawa; Takahiro Arakawa; Yoshiyuki Ishii; Daisuke Sasaki; Hidemasa Bono; Shinji Kondo; Yuichi Sugahara; Rintaro Saito; Naoki Osato; Shiro Fukuda; Kenjiro Sato; Akira Watahiki; Tomoko Hirozane-Kishikawa; Mari Nakamura; Yuko Shibata; Ayako Yasunishi; Noriko Kikuchi; Atsushi Yoshiki; Moriaki Kusakabe; Stefano Gustincich; Kirk Beisel; William Pavan; Vassilis Aidinis; Akira Nakagawara; William A Held; Hiroo Iwata; Tomohiro Kono; Hiromitsu Nakauchi; Paul Lyons; Christine Wells; David A Hume; Michela Fagiolini; Takao K Hensch; Michelle Brinkmeier; Sally Camper; Junji Hirota; Peter Mombaerts; Masami Muramatsu; Yasushi Okazaki; Jun Kawai; Yoshihide Hayashizaki
Journal:  Genome Res       Date:  2003-06       Impact factor: 9.043

Review 10.  Transcription regulation and animal diversity.

Authors:  Michael Levine; Robert Tjian
Journal:  Nature       Date:  2003-07-10       Impact factor: 49.962
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.