Literature DB >> 19377890

IRS2 variants and syndromes of severe insulin resistance.

W E Bottomley, M A Soos, C Adams, T Guran, T A Howlett, A Mackie, J Miell, J P Monson, R Temple, Y Tenenbaum-Rakover, J Tymms, D B Savage, R K Semple, S O'Rahilly, I Barroso.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19377890      PMCID： PMC2680062          DOI： 10.1007/s00125-009-1345-4

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


× No keyword cloud information.
  9 in total

1.  Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians.

Authors:  D Bernal; K Almind; L Yenush; M Ayoub; Y Zhang; L Rosshani; C Larsson; O Pedersen; M F White
Journal:  Diabetes       Date:  1998-06       Impact factor: 9.461

2.  New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes.

Authors:  H Wang; J Rissanen; R Miettinen; P Kärkkäinen; P Kekäläinen; J Kuusisto; L Mykkänen; P Karhapää; M Laakso
Journal:  Diabetes       Date:  2001-08       Impact factor: 9.461

3.  Disruption of IRS-2 causes type 2 diabetes in mice.

Authors:  D J Withers; J S Gutierrez; H Towery; D J Burks; J M Ren; S Previs; Y Zhang; D Bernal; S Pons; G I Shulman; S Bonner-Weir; M F White
Journal:  Nature       Date:  1998-02-26       Impact factor: 49.962

4.  Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

Authors:  K Almind; S K Frederiksen; D Bernal; T Hansen; L Ambye; S Urhammer; C T Ekstrøm; L Berglund; R Reneland; H Lithell; M F White; E Van Obberghen; O Pedersen
Journal:  Diabetologia       Date:  1999-10       Impact factor: 10.122

5.  Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

Authors:  Rossella D'Alfonso; Maria Adelaide Marini; Lucia Frittitta; Roberto Sorge; Simona Frontoni; Ottavia Porzio; Luisa Marina Mariani; Davide Lauro; Sergio Gambardella; Vincenzo Trischitta; Massimo Federici; Renato Lauro; Giorgio Sesti
Journal:  J Clin Endocrinol Metab       Date:  2003-01       Impact factor: 5.958

6.  Identification of a single nucleotide polymorphism showing no insulin-mediated suppression of the promoter activity in the human insulin receptor substrate 2 gene.

Authors:  K Iwamoto; H Mori; H Okazawa; M Hashiramoto; M Kasuga
Journal:  Diabetologia       Date:  2002-06-19       Impact factor: 10.122

7.  A family with severe insulin resistance and diabetes due to a mutation in AKT2.

Authors:  Stella George; Justin J Rochford; Christian Wolfrum; Sarah L Gray; Sven Schinner; Jenny C Wilson; Maria A Soos; Peter R Murgatroyd; Rachel M Williams; Carlo L Acerini; David B Dunger; David Barford; A Margot Umpleby; Nicholas J Wareham; Huw Alban Davies; Alan J Schafer; Markus Stoffel; Stephen O'Rahilly; Inês Barroso
Journal:  Science       Date:  2004-05-28       Impact factor: 47.728

8.  Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.

Authors:  Karen Tan; Wendy A Kimber; Jian'an Luan; Maria A Soos; Robert K Semple; Nicholas J Wareham; Stephen O'Rahilly; Inês Barroso
Journal:  Diabetes       Date:  2007-03       Impact factor: 9.461

9.  Digenic inheritance of severe insulin resistance in a human pedigree.

Authors:  David B Savage; Maura Agostini; Inês Barroso; Mark Gurnell; Jian'an Luan; Aline Meirhaeghe; Anne-Helen Harding; Gudrun Ihrke; Odelia Rajanayagam; Maria A Soos; Stella George; Dirk Berger; E Louise Thomas; Jimmy D Bell; Karim Meeran; Richard J Ross; Antonio Vidal-Puig; Nicholas J Wareham; Stephen O'Rahilly; V Krishna K Chatterjee; Alan J Schafer
Journal:  Nat Genet       Date:  2002-07-15       Impact factor: 38.330
  9 in total
  3 in total

1.  Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children.

Authors:  Nancy F Butte; V Saroja Voruganti; Shelley A Cole; Karin Haack; Anthony G Comuzzie; Donna M Muzny; David A Wheeler; Kyle Chang; Alicia Hawes; Richard A Gibbs
Journal:  Physiol Genomics       Date:  2011-07-19       Impact factor: 3.107

2.  Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy.

Authors:  Michelle B Hookham; Helen C O'Donovan; Rachel H Church; Annie Mercier-Zuber; Lucilla Luzi; Simon P Curran; Rosemarie M Carew; Alejandra Droguett; Sergio Mezzano; Markus Schubert; Morris F White; John K Crean; Derek P Brazil
Journal:  FEBS J       Date:  2013-05-29       Impact factor: 5.542

3.  Novel insulin receptor substrate 1 and 2 variants in breast and colorectal cancer.

Authors:  Diana Liberata Esposito; Fabio Verginelli; Sonia Toracchio; Sandra Mammarella; Laura De Lellis; Cinzia Vanni; Antonio Russo; Renato Mariani-Costantini; Alessandro Cama
Journal:  Oncol Rep       Date:  2013-07-18       Impact factor: 3.906
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.