BACKGROUND: A 63-year-old man presented with class II anginal symptoms. INVESTIGATIONS: Cardiac catheterization, intravascular ultrasound (IVUS) virtual histology, optical coherence tomography and off-line palpography. DIAGNOSIS: The patient was diagnosed as having a culprit lesion in the left circumflex artery and a vulnerable plaque in the left anterior descending artery. MANAGEMENT: The culprit lesion was treated with two overlapping drug-eluting stents. The vulnerable plaque was then treated with a self-expanding stent tailored to shield vulnerable plaques (vProtect Luminal Shield). After dilatation of the stent with a low-pressure balloon, IVUS and optical coherence tomography showed excellent apposition of the stent to the vessel wall, with no signs of tissue prolapse or edge dissections. At the 6-month follow-up appointment, the stent showed complete tissue coverage without signs of in-stent restenosis. CONCLUSIONS: Six months of follow-up has demonstrated that a patient with an IVUS-derived, thin capped fibroatheroma was successfully treated with a stent tailored to shield vulnerable plaques.
BACKGROUND: A 63-year-old man presented with class II anginal symptoms. INVESTIGATIONS: Cardiac catheterization, intravascular ultrasound (IVUS) virtual histology, optical coherence tomography and off-line palpography. DIAGNOSIS: The patient was diagnosed as having a culprit lesion in the left circumflex artery and a vulnerable plaque in the left anterior descending artery. MANAGEMENT: The culprit lesion was treated with two overlapping drug-eluting stents. The vulnerable plaque was then treated with a self-expanding stent tailored to shield vulnerable plaques (vProtect Luminal Shield). After dilatation of the stent with a low-pressure balloon, IVUS and optical coherence tomography showed excellent apposition of the stent to the vessel wall, with no signs of tissue prolapse or edge dissections. At the 6-month follow-up appointment, the stent showed complete tissue coverage without signs of in-stent restenosis. CONCLUSIONS: Six months of follow-up has demonstrated that a patient with an IVUS-derived, thin capped fibroatheroma was successfully treated with a stent tailored to shield vulnerable plaques.
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Authors: Shann S Yu; Ryan A Ortega; Brendan W Reagan; John A McPherson; Hak-Joon Sung; Todd D Giorgio Journal: Wiley Interdiscip Rev Nanomed Nanobiotechnol Date: 2011-08-10
Authors: Christian J Kastrup; Matthias Nahrendorf; Jose Luiz Figueiredo; Haeshin Lee; Swetha Kambhampati; Timothy Lee; Seung-Woo Cho; Rostic Gorbatov; Yoshiko Iwamoto; Tram T Dang; Partha Dutta; Ju Hun Yeon; Hao Cheng; Christopher D Pritchard; Arturo J Vegas; Cory D Siegel; Samantha MacDougall; Michael Okonkwo; Anh Thai; James R Stone; Arthur J Coury; Ralph Weissleder; Robert Langer; Daniel G Anderson Journal: Proc Natl Acad Sci U S A Date: 2012-12-11 Impact factor: 11.205
Authors: Salvatore Brugaletta; Hector M Garcia-Garcia; Zhu Jun Shen; Josep Gomez-Lara; Roberto Diletti; Giovanna Sarno; Nieves Gonzalo; William Wijns; Bernard de Bruyne; Fernando Alfonso; Patrick W Serruys Journal: Int J Cardiovasc Imaging Date: 2011-02-19 Impact factor: 2.357