Literature DB >> 19376714

Development of a tandem-electrostatic-quadrupole accelerator facility for BNCT.

A J Kreiner1, V Thatar Vento, P Levinas, J Bergueiro, H Di Paolo, A A Burlon, J M Kesque, A A Valda, M E Debray, H R Somacal, D M Minsky, L Estrada, A Hazarabedian, F Johann, J C Suarez Sandin, W Castell, J Davidson, M Davidson, Y Giboudot, M Repetto, M Obligado, J P Nery, H Huck, M Igarzabal, A Fernandez Salares.   

Abstract

In this work we describe the present status of an ongoing project to develop a tandem-electrostatic-quadrupole (TESQ) accelerator facility for accelerator-based (AB) BNCT at the Atomic Energy Commission of Argentina in Buenos Aires. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction slightly beyond its resonance at 2.25 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the (7)Li(p,n)(7)Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. An electrostatic machine is the technologically simplest and cheapest solution for optimized AB-BNCT. The machine being designed and constructed is a folded TESQ with a high-voltage terminal at 1.2 MV intended to work in air. Such a machine is conceptually shown to be capable of transporting and accelerating a 30 mA proton beam to 2.4 MeV. The general geometric layout, its associated electrostatic fields, and the acceleration tube are simulated using a 3D finite element procedure. The design and construction of the ESQ modules is discussed and their electrostatic fields are investigated. Beam transport calculations through the accelerator are briefly mentioned. Likewise, work related to neutron production targets, strippers, beam shaping assembly and patient treatment room is briefly described.

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Year:  2009        PMID: 19376714     DOI: 10.1016/j.apradiso.2009.03.084

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  1 in total

1.  A Novel Approach to Design and Evaluate BNCT Neutron Beams Combining Physical, Radiobiological, and Dosimetric Figures of Merit.

Authors:  Ian Postuma; Sara González; Maria S Herrera; Lucas Provenzano; Michele Ferrarini; Chiara Magni; Nicoletta Protti; Setareh Fatemi; Valerio Vercesi; Giuseppe Battistoni; Umberto Anselmi Tamburini; Yuan Hao Liu; Leena Kankaanranta; Hanna Koivunoro; Saverio Altieri; Silva Bortolussi
Journal:  Biology (Basel)       Date:  2021-02-26
  1 in total

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