Literature DB >> 19376060

A p75(NTR) pivoting paradigm propels perspicacity.

Philip A Barker1.   

Abstract

The p75 neurotrophin receptor (p75(NTR)) is involved in numerous neuronal signaling paths but its fundamental signaling mechanisms are unknown. In this issue of Neuron, Vilar et al. show that p75NTR functions as a covalently crosslinked dimer to transduce NGF-induced signaling events.

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Year:  2009        PMID: 19376060     DOI: 10.1016/j.neuron.2009.04.005

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  5 in total

1.  Stoichiometry counts.

Authors:  Moses V Chao
Journal:  Proc Natl Acad Sci U S A       Date:  2019-09-16       Impact factor: 11.205

2.  Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor.

Authors:  Marçal Vilar; Ioannis Charalampopoulos; Rajappa S Kenchappa; Alessandra Reversi; Joanna M Klos-Applequist; Esra Karaca; Anastasia Simi; Carlos Spuch; Soyoung Choi; Wilma J Friedman; Johan Ericson; Giampietro Schiavo; Bruce D Carter; Carlos F Ibáñez
Journal:  J Cell Sci       Date:  2009-08-25       Impact factor: 5.285

3.  Experimental verification of a predicted intronic microRNA in human NGFR gene with a potential pro-apoptotic function.

Authors:  Sepideh Parsi; Bahram M Soltani; Ebrahim Hosseini; Samaneh E Tousi; Seyed J Mowla
Journal:  PLoS One       Date:  2012-04-27       Impact factor: 3.240

4.  Polysialylated Neural Cell Adhesion Molecule Protects Against Light-Induced Retinal Degeneration.

Authors:  Margaret Po-Shan Luke; Terry L LeVatte; Urs Rutishauser; François Tremblay; David B Clarke
Journal:  Invest Ophthalmol Vis Sci       Date:  2016-09-01       Impact factor: 4.799

5.  Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation.

Authors:  Agustin Anastasia; Phillip A Barker; Moses V Chao; Barbara L Hempstead
Journal:  J Neurosci       Date:  2015-08-26       Impact factor: 6.167

  5 in total

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