Literature DB >> 19375514

The calcium/NFAT pathway: role in development and function of regulatory T cells.

Masatsugu Oh-hora1, Anjana Rao.   

Abstract

Calcium signals are essential for diverse cellular functions in the immune system. Sustained Ca(2+) entry is necessary for complete and long-lasting activation of calcineurin/NFAT pathways. A growing number of studies have emphasized that Ca(2+)/calcineurin/NFAT pathway is crucial for both development and function of regulatory T cells.

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Year:  2009        PMID： 19375514      PMCID： PMC2696553          DOI： 10.1016/j.micinf.2009.04.008

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  62 in total

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Authors:  H Turner; J P Kinet
Journal:  Nature       Date:  1999-11-25       Impact factor: 49.962

2.  Control of regulatory T cell development by the transcription factor Foxp3.

Authors:  Shohei Hori; Takashi Nomura; Shimon Sakaguchi
Journal:  Science       Date:  2003-01-09       Impact factor: 47.728

3.  Calcineurin B1 is essential for positive but not negative selection during thymocyte development.

Authors:  Joel R Neilson; Monte M Winslow; Eun Mi Hur; Gerald R Crabtree
Journal:  Immunity       Date:  2004-03       Impact factor: 31.745

Review 4.  Transcriptional regulation by calcium, calcineurin, and NFAT.

Authors:  Patrick G Hogan; Lin Chen; Julie Nardone; Anjana Rao
Journal:  Genes Dev       Date:  2003-09-15       Impact factor: 11.361

5.  Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins.

Authors:  R T Williams; S S Manji; N J Parker; M S Hancock; L Van Stekelenburg; J P Eid; P V Senior; J S Kazenwadel; T Shandala; R Saint; P J Smith; M A Dziadek
Journal:  Biochem J       Date:  2001-08-01       Impact factor: 3.857

6.  Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.

Authors:  Jason D Fontenot; Marc A Gavin; Alexander Y Rudensky
Journal:  Nat Immunol       Date:  2003-03-03       Impact factor: 25.606

7.  Defective T cell development and function in calcineurin A beta -deficient mice.

Authors:  Orlando F Bueno; Eric B Brandt; Marc E Rothenberg; Jeffery D Molkentin
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-28       Impact factor: 11.205

8.  Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice.

Authors:  Noriko Sakaguchi; Takeshi Takahashi; Hiroshi Hata; Takashi Nomura; Tomoyuki Tagami; Sayuri Yamazaki; Toshiko Sakihama; Takaji Matsutani; Izumi Negishi; Syuichi Nakatsuru; Shimon Sakaguchi
Journal:  Nature       Date:  2003-11-27       Impact factor: 49.962

9.  Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice.

Authors:  S Sakaguchi; N Sakaguchi
Journal:  J Exp Med       Date:  1988-04-01       Impact factor: 14.307

10.  CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

Authors:  Hyoung-Pyo Kim; Warren J Leonard
Journal:  J Exp Med       Date:  2007-06-25       Impact factor: 14.307
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  36 in total

1.  Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay.

Authors:  Bhavin S Parekh; Elaine Berger; Sharon Sibley; Suntara Cahya; Liqun Xiao; Melinda Ann LaCerte; Peter Vaillancourt; Scott Wooden; Dennis Gately
Journal:  MAbs       Date:  2012-04-26       Impact factor: 5.857

2.  GnRH regulation of Jun and Atf3 requires calcium, calcineurin, and NFAT.

Authors:  April K Binder; Jean C Grammer; Maria K Herndon; Julie D Stanton; John H Nilson
Journal:  Mol Endocrinol       Date:  2012-03-22

3.  EphA2 stimulates VCAM-1 expression through calcium-dependent NFAT1 activity.

Authors:  Steven Daniel Funk; Alexandra C Finney; Arif Yurdagul; Christopher B Pattillo; A Wayne Orr
Journal:  Cell Signal       Date:  2018-05-21       Impact factor: 4.315

4.  Cyclosporine A-Mediated IL-6 Expression Promotes Neural Induction in Pluripotent Stem Cells.

Authors:  Ashwathnarayan Ashwini; Sushma S Naganur; Bhaskar Smitha; Preethi Sheshadri; Jyothi Prasanna; Anujith Kumar
Journal:  Mol Neurobiol       Date:  2017-06-16       Impact factor: 5.590

5.  NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.

Authors:  Gunjan D Manocha; Atreyi Ghatak; Kendra L Puig; Susan D Kraner; Christopher M Norris; Colin K Combs
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

Review 6.  Transplant trials with Tregs: perils and promises.

Authors:  Qizhi Tang; Flavio Vincenti
Journal:  J Clin Invest       Date:  2017-06-30       Impact factor: 14.808

7.  PEG-Anthracene Hydrogels as an On-Demand Stiffening Matrix To Study Mechanobiology.

Authors:  Kemal Arda Günay; Tova L Ceccato; Jason S Silver; Kendra L Bannister; Olivia J Bednarski; Leslie A Leinwand; Kristi S Anseth
Journal:  Angew Chem Int Ed Engl       Date:  2019-06-11       Impact factor: 15.336

8.  Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.

Authors:  Martin Vaeth; Ulrike Schliesser; Gerd Müller; Sonja Reissig; Kazuki Satoh; Andrea Tuettenberg; Helmut Jonuleit; Ari Waisman; Martin R Müller; Edgar Serfling; Birgit S Sawitzki; Friederike Berberich-Siebelt
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-18       Impact factor: 11.205

9.  Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer.

Authors:  Dhifaf Sarhan; Caroline Leijonhufvud; Shannon Murray; Kristina Witt; Christina Seitz; Majken Wallerius; Hanjing Xie; Anders Ullén; Ulrika Harmenberg; Elisabet Lidbrink; Charlotte Rolny; John Andersson; Andreas Lundqvist
Journal:  Oncoimmunology       Date:  2017-06-14       Impact factor: 8.110

10.  Role of Ca/CaN/NFAT signaling in IL-4 expression by splenic lymphocytes exposed to phthalate (2-ethylhexyl) ester in spleen lymphocytes.

Authors:  Xiucong Pei; Zhiwen Duan; Mingyue Ma; Yuming Zhang; Li Guo
Journal:  Mol Biol Rep       Date:  2014-01-14       Impact factor: 2.316
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