| Literature DB >> 193739 |
P W Hochachka, J R Neely, W R Driedzic.
Abstract
This essay illustrates the ways in which beta-oxidation and the citric acid cycle interact. These included: 1) competition for CoASH, 2) competition for NAD+, and 3) competition for FADH2 oxidation. By means of the above, the cell is able to maintain a precise coordination between the activation of fatty acids in the cytosol, beta-oxidation in the mitochondria, and the complete oxidation of acetyl-CoA to CO2 via the citric acid cycle throughout a wide range of energy demands and oxygen availability.Entities:
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Year: 1977 PMID: 193739
Source DB: PubMed Journal: Fed Proc ISSN: 0014-9446