Literature DB >> 19373796

Rolling-circle amplification: unshared advantages in miRNA detection.

Saskia Neubacher1, Christoph Arenz.   

Abstract

Roll with it: The quantitative analysis of specific miRNAs from biological samples is very likely to revolutionize diagnostics of human disease. A novel method for miRNA analysis employing rolling-circle amplification (RCA) can homogeneously detect miRNA, even at concentrations as low as 10 fM. The use of T4 RNA ligase 2 (T4 RnL2) at elevated temperatures enables very good discrimination of miRNAs differing by a single nucleotide.

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Year:  2009        PMID： 19373796     DOI： 10.1002/cbic.200900116

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


  5 in total

1.  Evolving methods for single nucleotide polymorphism detection: Factor V Leiden mutation detection.

Authors:  Herin Oh; Cassandra L Smith
Journal:  J Clin Lab Anal       Date:  2011       Impact factor: 2.352

Review 2.  A Combinational Approach for More Efficient miRNA Biosensing.

Authors:  Cheolho Lee
Journal:  Curr Genomics       Date:  2022-04-07       Impact factor: 2.689

3.  Amplified microRNA detection by templated chemistry.

Authors:  Emily M Harcourt; Eric T Kool
Journal:  Nucleic Acids Res       Date:  2012-01-25       Impact factor: 16.971

Review 4.  Micro- and nanosensors for detecting blood pathogens and biomarkers at different points of sepsis care.

Authors:  Alejandra Alba-Patiño; Andreu Vaquer; Enrique Barón; Steven M Russell; Marcio Borges; Roberto de la Rica
Journal:  Mikrochim Acta       Date:  2022-01-26       Impact factor: 5.833

5.  A Fast and Easy Method for Specific Detection of Circular RNA by Rolling-Circle Amplification.

Authors:  Marcel Boss; Christoph Arenz
Journal:  Chembiochem       Date:  2019-11-27       Impact factor: 3.164
  5 in total

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