BACKGROUND: Merkel Cell Carcinoma (MCC) is a rare neurendocrine tumor of cutaneous origin. METHODS AND RESULTS: A 79-year-old woman was seen with a neck lump and a lesion in the left nasal vestibule. Biopsy of the lesion revealed a primary neurendocrine MCC of the skin of the nasal vestibule with metastases to the cervical lymph nodes. The patient decided against any further active treatment. Follow-up of patient for 30 months showed spontaneous regression of the lesions without any active treatment. CONCLUSIONS: Although spontaneous resolution of MCC has been described for other head neck sites, there has not been any published case of nasal MCC regression. We present this rare case of nasal MCC with neck metastases and its regression.
BACKGROUND:Merkel Cell Carcinoma (MCC) is a rare neurendocrine tumor of cutaneous origin. METHODS AND RESULTS: A 79-year-old woman was seen with a neck lump and a lesion in the left nasal vestibule. Biopsy of the lesion revealed a primary neurendocrine MCC of the skin of the nasal vestibule with metastases to the cervical lymph nodes. The patient decided against any further active treatment. Follow-up of patient for 30 months showed spontaneous regression of the lesions without any active treatment. CONCLUSIONS: Although spontaneous resolution of MCC has been described for other head neck sites, there has not been any published case of nasal MCC regression. We present this rare case of nasal MCC with neck metastases and its regression.
Authors: Sandra Catharina Petronella Jansen; Christine P M Groeneveld-Haenen; Paul J J M Klinkhamer; Rudi M H Roumen Journal: BMJ Case Rep Date: 2015-02-25
Authors: Raffaele Longo; Oana Balasanu; Mathilde Chastenet de Castaing; Eric Chatelain; Mohammed Yacoubi; Marco Campitiello; Nathalie Marcon; Francesca Plastino Journal: Am J Case Rep Date: 2018-12-04