J S Elborn1, M Hodson, C Bertram. 1. Respiratory Medicine Research Group, Queen's University, Belfast City Hospital, Ground Floor, Lisburn Rd, Belfast, BT9 7AB, UK. stuart.elborn@bch.n-i.nhs.uk
Abstract
BACKGROUND: Several guidelines on infection control and treatment of infection exist for cystic fibrosis (CF) caregivers, although the extent of implementation is variable. METHODS: Adherence to European Consensus Guidelines for CF was studied by sending surveys to named healthcare professionals in 487 European CF centres/units. Qualitative data analysis was performed. RESULTS: A total of 177/547 (32%) surveys were returned. Infection control policies were implemented by most (77%) respondents. Separation of patients with Burkholderia cepacia was more common in adults (95%) than children (9%), and was implemented by 53% of respondents for Pseudomonas aeruginosa. Nebulised colistin plus oral ciprofloxacin was the most common (43%) therapy for P. aeruginosa infection. First infections of P. aeruginosa were usually treated with inhaled tobramycin; 41% of repondents did not intervene until lung function deteriorated. Most exacerbations were treated for less than the recommended period. CONCLUSIONS: European Consensus Guidelines are widely adhered to. Areas for improvement include: initiating therapy for exacerbations early, separating infected patients and optimising duration of antibiotic therapy.
BACKGROUND: Several guidelines on infection control and treatment of infection exist for cystic fibrosis (CF) caregivers, although the extent of implementation is variable. METHODS: Adherence to European Consensus Guidelines for CF was studied by sending surveys to named healthcare professionals in 487 European CF centres/units. Qualitative data analysis was performed. RESULTS: A total of 177/547 (32%) surveys were returned. Infection control policies were implemented by most (77%) respondents. Separation of patients with Burkholderia cepacia was more common in adults (95%) than children (9%), and was implemented by 53% of respondents for Pseudomonas aeruginosa. Nebulised colistin plus oral ciprofloxacin was the most common (43%) therapy for P. aeruginosa infection. First infections of P. aeruginosa were usually treated with inhaled tobramycin; 41% of repondents did not intervene until lung function deteriorated. Most exacerbations were treated for less than the recommended period. CONCLUSIONS: European Consensus Guidelines are widely adhered to. Areas for improvement include: initiating therapy for exacerbations early, separating infectedpatients and optimising duration of antibiotic therapy.
Authors: Muhammad-Hariri Mustafa; Hussein Chalhoub; Olivier Denis; Ariane Deplano; Anne Vergison; Hector Rodriguez-Villalobos; Michael M Tunney; J Stuart Elborn; Barbara C Kahl; Hamidou Traore; Francis Vanderbist; Paul M Tulkens; Françoise Van Bambeke Journal: Antimicrob Agents Chemother Date: 2016-10-21 Impact factor: 5.191
Authors: S L Heltshe; U Khan; V Beckett; A Baines; J Emerson; D B Sanders; R L Gibson; W Morgan; M Rosenfeld Journal: J Cyst Fibros Date: 2017-10-28 Impact factor: 5.482
Authors: Zhe Hui Hoo; Frank Peter Edenborough; Rachael Curley; Laura Prtak; Jane Dewar; Mark Ivan Allenby; Julia Anne Nightingale; Martin James Wildman Journal: Eur J Clin Microbiol Infect Dis Date: 2018-01-06 Impact factor: 3.267
Authors: Maite E Houwing; Marit Buddenbaum; Thijs C J Verheul; Anne P J de Pagter; Jacobus N J Philipsen; Jan A Hazelzet; Marjon H Cnossen Journal: BMC Health Serv Res Date: 2021-03-12 Impact factor: 2.655