| Literature DB >> 19372040 |
Ying-Kai Fu1, Chia-Jung Chang, Kuan-Yin Chen, Li-Chung Hwang, Kuo-Hung Wu, Kang-Wei Chang, Meei-Ling Jan, Chia-Chieh Chen, Chih-Hsien Chang.
Abstract
Changes in regional metabolic activities induced by middle cerebral artery occlusion (MCAO) can influence patient outcome. Our aim was to demonstrate in a rat model that (18)F-FDG with positron emission tomography (PET) imaging is a quantitative, reproducible approach for identifying acute and sub-acute metabolic variations in infarct regions. We found that imaging with (18)F-FDG/PET enabled detection and quantification of ischemia-induced metabolic deficits and provided a sensitive and reliable means of assessing cerebral ischemic lesions compared with conventional neurological scoring systems in rodents.Entities:
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Year: 2009 PMID： 19372040 DOI： 10.1016/j.apradiso.2009.03.002
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513