| Literature DB >> 19371791 |
Abstract
IL-17 was discovered in 1995/96 as a T cell derived cytokine with effects on inflammation and neutrophil activation. In 2006, the precise cell source of IL-17 was identified in the mouse, and these cells were named Th17 cells. They play a role in various human diseases associated with inflammation and destruction such as rheumatoid arthritis, psoriasis, Crohn's disease, multiple sclerosis, where IL-17 can be seen as a therapeutic target.Entities:
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Year: 2009 PMID： 19371791 DOI： 10.1016/j.micinf.2009.04.003
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700