BACKGROUND: Hemolytic uremic syndrome (HUS) is commonly caused by hemorrhagic colitis with Shiga toxin-producing Escherichia coli O-157. Central nervous system (CNS) involvements, including seizures, encephalopathy and brain infarction, are serious complications, but there are no useful scores for the prediction of CNS complications. METHODS: Routine laboratory data at onset of HUS were re-evaluated in 14 patients to find useful parameters for the prediction of CNS complication. RESULTS: Serum sodium and total protein were significantly lower and C-reactive protein (CRP) and white blood cell counts were significantly higher in patients with CNS complications than in patients without. A cumulated score, SCWP score (sodium, CRP, white blood cell count, and total protein) discriminated better between patients with/without CNS complications than individual values. CONCLUSIONS: SCWP score would be useful for prediction of CNS complications.
BACKGROUND:Hemolytic uremic syndrome (HUS) is commonly caused by hemorrhagic colitis with Shiga toxin-producing Escherichia coli O-157. Central nervous system (CNS) involvements, including seizures, encephalopathy and brain infarction, are serious complications, but there are no useful scores for the prediction of CNS complications. METHODS: Routine laboratory data at onset of HUS were re-evaluated in 14 patients to find useful parameters for the prediction of CNS complication. RESULTS: Serum sodium and total protein were significantly lower and C-reactive protein (CRP) and white blood cell counts were significantly higher in patients with CNS complications than in patients without. A cumulated score, SCWP score (sodium, CRP, white blood cell count, and total protein) discriminated better between patients with/without CNS complications than individual values. CONCLUSIONS: SCWP score would be useful for prediction of CNS complications.
Authors: Frank Donnerstag; Xiaoqi Ding; Lars Pape; Eva Bültmann; Thomas Lücke; Jan Zajaczek; Ludwig Hoy; Anibh Martin Das; Heinrich Lanfermann; Jochen Ehrich; Hans Hartmann Journal: Eur Radiol Date: 2011-10-08 Impact factor: 5.315
Authors: Bettina Wöchtl; Florian Gunzer; Wilhelm Gerner; Hagen Gasse; Michaela Koch; Zoltán Bagó; Martin Ganter; Herbert Weissenböck; Nora Dinhopl; Sina M Coldewey; Alexandra von Altrock; Karl-Heinz Waldmann; Armin Saalmüller; Kurt Zimmermann; Jörg Steinmann; Jan Kehrmann; Ludger Klein-Hitpass; Jochen Blom; Ralf Ehricht; Ines Engelmann; Isabel Hennig-Pauka Journal: Gut Pathog Date: 2017-05-25 Impact factor: 4.181
Authors: Alexandra Kleimann; Sermin Toto; Christian K Eberlein; Jan T Kielstein; Stefan Bleich; Helge Frieling; Marcel Sieberer Journal: PLoS One Date: 2014-07-09 Impact factor: 3.240