| Literature DB >> 19371090 |
Thomas Jensen1, Robert Madsen.
Abstract
An atom-economical and solvent-free catalytic procedure for the mono-3-alkylation of oxindole with alcohols is described. The reaction is mediated by the in situ generated catalyst from RuCl(3) x xH(2)O and PPh(3) in the presence of sodium hydroxide. The reactions proceed in good to excellent yields with a wide range of aromatic, heteroaromatic, and aliphatic alcohols.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19371090 DOI: 10.1021/jo900341w
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354