Literature DB >> 19371090

Ruthenium-catalyzed alkylation of oxindole with alcohols.

Thomas Jensen1, Robert Madsen.   

Abstract

An atom-economical and solvent-free catalytic procedure for the mono-3-alkylation of oxindole with alcohols is described. The reaction is mediated by the in situ generated catalyst from RuCl(3) x xH(2)O and PPh(3) in the presence of sodium hydroxide. The reactions proceed in good to excellent yields with a wide range of aromatic, heteroaromatic, and aliphatic alcohols.

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Year:  2009        PMID: 19371090     DOI: 10.1021/jo900341w

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  4 in total

1.  Cytotoxic activities of substituted 3-(3,4,5-trimethoxybenzylidene)-1,3-dihydroindol-2-ones and studies on their mechanisms of action.

Authors:  Aldo Andreani; Massimiliano Granaiola; Alessandra Locatelli; Rita Morigi; Mirella Rambaldi; Lucilla Varoli; Francesco Vieceli Dalla Sega; Cecilia Prata; Tam L Nguyen; Ruoli Bai; Ernest Hamel
Journal:  Eur J Med Chem       Date:  2013-04-03       Impact factor: 6.514

2.  A nickel phosphide nanoalloy catalyst for the C-3 alkylation of oxindoles with alcohols.

Authors:  Shu Fujita; Kohei Imagawa; Sho Yamaguchi; Jun Yamasaki; Seiji Yamazoe; Tomoo Mizugaki; Takato Mitsudome
Journal:  Sci Rep       Date:  2021-05-21       Impact factor: 4.379

3.  Manganese-Catalyzed α-Alkylation of Ketones, Esters, and Amides Using Alcohols.

Authors:  Subrata Chakraborty; Prosenjit Daw; Yehoshoa Ben David; David Milstein
Journal:  ACS Catal       Date:  2018-10-02       Impact factor: 13.084

4.  Iron-Catalyzed Borrowing Hydrogen C-Alkylation of Oxindoles with Alcohols.

Authors:  Mubarak B Dambatta; Kurt Polidano; Alexander D Northey; Jonathan M J Williams; Louis C Morrill
Journal:  ChemSusChem       Date:  2019-05-07       Impact factor: 8.928

  4 in total

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