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Literature DB >> 19369659

Crohn's disease, autophagy, and the Paneth cell.

Daniel J Klionsky¹.

Abstract

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2009 PMID： 19369659 PMCID： PMC2832908 DOI： 10.1056/NEJMcibr0810347

Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245

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5 in total

1. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.

Authors: Ken Cadwell; Khushbu K Patel; Masaaki Komatsu; Herbert W Virgin; Thaddeus S Stappenbeck
Journal: Autophagy Date: 2009-02-08 Impact factor: 16.016

2. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.

Authors: Tatsuya Saitoh; Naonobu Fujita; Myoung Ho Jang; Satoshi Uematsu; Bo-Gie Yang; Takashi Satoh; Hiroko Omori; Takeshi Noda; Naoki Yamamoto; Masaaki Komatsu; Keiji Tanaka; Taro Kawai; Tohru Tsujimura; Osamu Takeuchi; Tamotsu Yoshimori; Shizuo Akira
Journal: Nature Date: 2008-10-05 Impact factor: 49.962

3. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.

Authors: Ken Cadwell; John Y Liu; Sarah L Brown; Hiroyuki Miyoshi; Joy Loh; Jochen K Lennerz; Chieko Kishi; Wumesh Kc; Javier A Carrero; Steven Hunt; Christian D Stone; Elizabeth M Brunt; Ramnik J Xavier; Barry P Sleckman; Ellen Li; Noboru Mizushima; Thaddeus S Stappenbeck; Herbert W Virgin
Journal: Nature Date: 2008-10-05 Impact factor: 49.962

4. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.

Authors: Jochen Hampe; Andre Franke; Philip Rosenstiel; Andreas Till; Markus Teuber; Klaus Huse; Mario Albrecht; Gabriele Mayr; Francisco M De La Vega; Jason Briggs; Simone Günther; Natalie J Prescott; Clive M Onnie; Robert Häsler; Bence Sipos; Ulrich R Fölsch; Thomas Lengauer; Matthias Platzer; Christopher G Mathew; Michael Krawczak; Stefan Schreiber
Journal: Nat Genet Date: 2006-12-31 Impact factor: 38.330

5. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.

Authors: Petric Kuballa; Alan Huett; John D Rioux; Mark J Daly; Ramnik J Xavier
Journal: PLoS One Date: 2008-10-13 Impact factor: 3.240

5 in total

23 in total

1. Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis.

Authors: Andrew A Maynard; Katerina Dvorak; Ludmila Khailova; Holly Dobrenen; Kelly M Arganbright; Melissa D Halpern; Ashish R Kurundkar; Akhil Maheshwari; Bohuslav Dvorak
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2010-06-10 Impact factor: 4.052

2. Genetics studies in ischaemic stroke.

Authors: Hugh S Markus
Journal: Transl Stroke Res Date: 2010-08-31 Impact factor: 6.829

3. Aging is associated with hypermethylation of autophagy genes in macrophages.

Authors: Hany Khalil; Mia Tazi; Kyle Caution; Amr Ahmed; Apurva Kanneganti; Kaivon Assani; Benjamin Kopp; Clay Marsh; Duaa Dakhlallah; Amal O Amer
Journal: Epigenetics Date: 2016-02-24 Impact factor: 4.528

4. Unravelling the genetics of ischaemic stroke.

Authors: Hugh S Markus
Journal: PLoS Med Date: 2010-03-02 Impact factor: 11.069

5. Impaired Autophagy in the Fibroblasts by Titanium Particles Increased the Release of CX3CL1 and Promoted the Chemotactic Migration of Monocytes.

Authors: Wen Wu; Lei Wang; Yuan-Qing Mao; Ke-Rong Dai; Yong-Qiang Hao
Journal: Inflammation Date: 2020-04 Impact factor: 4.092

Crohn's disease, autophagy, and the Paneth cell.

1. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.

2. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.

3. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.

4. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.

5. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.

1. Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis.

2. Genetics studies in ischaemic stroke.

3. Aging is associated with hypermethylation of autophagy genes in macrophages.

4. Unravelling the genetics of ischaemic stroke.

5. Impaired Autophagy in the Fibroblasts by Titanium Particles Increased the Release of CX3CL1 and Promoted the Chemotactic Migration of Monocytes.

6. Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis.

Review 7. Autophagy in immunity: implications in etiology of autoimmune/autoinflammatory diseases.

8. Structure of the WD40-domain of human ATG16L1.

9. The neutrophil respiratory burst and bacterial digestion in Crohn's disease.

10. Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.