BACKGROUND AND PURPOSE: Paragangliomas are highly vascularized usually benign neoplasms arising from nerve tissue. Endovascular preoperative embolization is used to facilitate surgery but is often not complete, due to tiny feeding arteries not feasible for selective catheterization. Our purpose was to evaluate angiographic and clinical outcome using Onyx for percutaneous glomus tumor embolization. MATERIALS AND METHODS: A consecutive series of 4 patients with 6 paragangliomas located at the bifurcation of the common carotid artery were treated with percutaneous embolization using Onyx as the sole embolic material. RESULTS: Complete devascularization of the 6 paragangliomas was achieved using a percutaneous embolization technique with Onyx as a sole agent, combined with an endovascular microballoon that offered protection of the internal carotid artery. CONCLUSIONS: Further documentation is necessary to prove the higher grade of devascularization of paragangliomas with Onyx compared with other embolic material and the associated potential to facilitate surgery. Nevertheless, Onyx seems to be safe when used percutaneously due to its lavalike pattern flow and its controllable properties, allowing slow tumor bed penetration.
BACKGROUND AND PURPOSE:Paragangliomas are highly vascularized usually benign neoplasms arising from nerve tissue. Endovascular preoperative embolization is used to facilitate surgery but is often not complete, due to tiny feeding arteries not feasible for selective catheterization. Our purpose was to evaluate angiographic and clinical outcome using Onyx for percutaneous glomus tumor embolization. MATERIALS AND METHODS: A consecutive series of 4 patients with 6 paragangliomas located at the bifurcation of the common carotid artery were treated with percutaneous embolization using Onyx as the sole embolic material. RESULTS: Complete devascularization of the 6 paragangliomas was achieved using a percutaneous embolization technique with Onyx as a sole agent, combined with an endovascular microballoon that offered protection of the internal carotid artery. CONCLUSIONS: Further documentation is necessary to prove the higher grade of devascularization of paragangliomas with Onyx compared with other embolic material and the associated potential to facilitate surgery. Nevertheless, Onyx seems to be safe when used percutaneously due to its lavalike pattern flow and its controllable properties, allowing slow tumor bed penetration.
Authors: Julius Griauzde; Joseph J Gemmete; Neeraj Chaudhary; Aditya S Pandey; Steven E Sullivan; Erin L McKean; Lawerence J Marentette Journal: Neuroradiology Date: 2013-06-22 Impact factor: 2.804
Authors: J J Gemmete; S Patel; A S Pandey; S E Sullivan; E L McKean; L J Marentette; N Chaudhary Journal: AJNR Am J Neuroradiol Date: 2012-04-12 Impact factor: 3.825
Authors: J J Gemmete; N Chaudhary; A Pandey; D Gandhi; S E Sullivan; L J Marentette; D B Chepeha; S A Ansari Journal: AJNR Am J Neuroradiol Date: 2009-12-24 Impact factor: 3.825
Authors: Nicolai El Hindy; Adrian Ringelstein; Michael Forsting; Ulrich Sure; Oliver Mueller Journal: World J Surg Oncol Date: 2013-07-11 Impact factor: 2.754