Literature DB >> 19369503

Metal-MACiE: a database of metals involved in biological catalysis.

Claudia Andreini1, Ivano Bertini, Gabriele Cavallaro, Gemma L Holliday, Janet M Thornton.   

Abstract

SUMMARY: Metal-MACiE is a new publicly available web-based database, held in MySQL, which aims to organize the available information on the properties and the roles of metals in the context of the catalytic mechanisms of metalloenzymes. Metal-MACiE, which currently covers 75% of metal-dependent enzyme commission (EC) sub-sub-classes and is continuously growing, exploits the existing MACiE database for the annotation of the reaction mechanisms. The two databases constitute complementary sources of information for enzymology, biochemistry and molecular pharmacology studies. AVAILABILITY: http://www.ebi.ac.uk/thornton-srv/databases/Metal_MACiE/home.html.

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Year:  2009        PMID: 19369503     DOI: 10.1093/bioinformatics/btp256

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  35 in total

1.  Activation of the Yeast UBI4 Polyubiquitin Gene by Zap1 Transcription Factor via an Intragenic Promoter Is Critical for Zinc-deficient Growth.

Authors:  Colin W MacDiarmid; Janet Taggart; Jeeyon Jeong; Kittikhun Kerdsomboon; David J Eide
Journal:  J Biol Chem       Date:  2016-07-18       Impact factor: 5.157

2.  Peroxiredoxin chaperone activity is critical for protein homeostasis in zinc-deficient yeast.

Authors:  Colin W MacDiarmid; Janet Taggart; Kittikhun Kerdsomboon; Michael Kubisiak; Supawee Panascharoen; Katherine Schelble; David J Eide
Journal:  J Biol Chem       Date:  2013-09-10       Impact factor: 5.157

Review 3.  Targeting Metalloenzymes for Therapeutic Intervention.

Authors:  Allie Y Chen; Rebecca N Adamek; Benjamin L Dick; Cy V Credille; Christine N Morrison; Seth M Cohen
Journal:  Chem Rev       Date:  2018-09-07       Impact factor: 60.622

4.  Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution.

Authors:  Marina V Omelchenko; Michael Y Galperin; Yuri I Wolf; Eugene V Koonin
Journal:  Biol Direct       Date:  2010-04-30       Impact factor: 4.540

Review 5.  Toward mechanistic classification of enzyme functions.

Authors:  Daniel E Almonacid; Patricia C Babbitt
Journal:  Curr Opin Chem Biol       Date:  2011-04-12       Impact factor: 8.822

6.  Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server.

Authors:  Heping Zheng; Mahendra D Chordia; David R Cooper; Maksymilian Chruszcz; Peter Müller; George M Sheldrick; Wladek Minor
Journal:  Nat Protoc       Date:  2013-12-19       Impact factor: 13.491

7.  Alterations in brain transition metals in Huntington disease: an evolving and intricate story.

Authors:  H Diana Rosas; Y Iris Chen; Gheorghe Doros; David H Salat; Nan-kuei Chen; Ken K Kwong; Ashley Bush; Jonathan Fox; Steven M Hersch
Journal:  Arch Neurol       Date:  2012-07

Review 8.  Magnesium magnetic isotope effects in microbiology.

Authors:  Ulyana G Letuta
Journal:  Arch Microbiol       Date:  2021-02-21       Impact factor: 2.552

9.  Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes: implications for classification of enzyme function.

Authors:  Daniel E Almonacid; Emmanuel R Yera; John B O Mitchell; Patricia C Babbitt
Journal:  PLoS Comput Biol       Date:  2010-03-12       Impact factor: 4.475

10.  The CoFactor database: organic cofactors in enzyme catalysis.

Authors:  Julia D Fischer; Gemma L Holliday; Janet M Thornton
Journal:  Bioinformatics       Date:  2010-08-02       Impact factor: 6.937

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