| Literature DB >> 19369355 |
Satoshi Kakugawa1, Masayuki Shimojima, Gabriele Neumann, Hideo Goto, Yoshihiro Kawaoka.
Abstract
In pro- and eukaryotic cells, RuvB-like protein 2 (RBL2) resolves Holliday junction recombination intermediates. Here, we identified RBL2 as a suppressor of influenza A virus replication. Human RBL2 appears to interfere with the oligomerization of the viral nucleoprotein, a critical step in the assembly of viral replication complexes.Entities:
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Year: 2009 PMID: 19369355 PMCID: PMC2698547 DOI: 10.1128/JVI.00293-09
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103