| Literature DB >> 19367383 |
Shoko Nakayama1, Taiji Yokote, Kichinosuke Kobayashi, Yuji Hirata, Toshikazu Akioka, Takuji Miyoshi, Takayuki Takubo, Motomu Tsuji, Toshiaki Hanafusa.
Abstract
A patient having acute myeloid leukemia (AML) with multilineage dysplasia, developed hyponatremia and showed all symptoms of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) through a mechanism similar to tumor lysis. Retrospective immunohistochemical analysis of blast cells was positive for antidiuretic hormone (ADH) protein. According to us, this is the first case report of SIADH in an AML patient with multilineage dysplasia, showing blast cells immunostained for ADH, which clearly demonstrated that the tumor cells produced ADH.Entities:
Mesh:
Year: 2009 PMID: 19367383 DOI: 10.1007/s12020-009-9171-5
Source DB: PubMed Journal: Endocrine ISSN: 1355-008X Impact factor: 3.633