Literature DB >> 19367309

Is hepcidin the star player in iron metabolism in chronic kidney disease?

Yasuhiro Hamada1, Masafumi Fukagawa.   

Abstract

It is well known that abnormal iron metabolism contributes to the development of anemia in chronic kidney disease (CKD) patients. Hepcidin is a circulating peptide produced in the liver that regulates efflux of iron from the cells. Ashby et al. measured the serum level of hepcidin using a new assay. Although the new assay produced mixed results and needs to be verified, these data suggest that hepcidin is not the only star player in iron metabolism in CKD.

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Year:  2009        PMID： 19367309     DOI： 10.1038/ki.2009.46

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  6 in total

1.  Effects of additional iron doses on hepcidin-25 level in hemodialysis patients without evident iron deficiency.

Authors:  Lavinia Oltiţa Brătescu; Liliana Bârsan; Liliana Gârneaţă; Ana Stanciu; Mariana Lipan; Simona Hildegard Stancu; Gabriel Mircescu
Journal:  Int Urol Nephrol       Date:  2014-03-29       Impact factor: 2.370

2.  Evaluation of hepcidin isoforms in hemodialysis patients by a proteomic approach based on SELDI-TOF MS.

Authors:  Natascia Campostrini; Annalisa Castagna; Federica Zaninotto; Valeria Bedogna; Nicola Tessitore; Albino Poli; Nicola Martinelli; Antonio Lupo; Oliviero Olivieri; Domenico Girelli
Journal:  J Biomed Biotechnol       Date:  2010-04-15

3.  Urine catalytic iron and neutrophil gelatinase-associated lipocalin as companion early markers of acute kidney injury after cardiac surgery: a prospective pilot study.

Authors:  Krittapoom Akrawinthawong; Michael K Shaw; Joshua Kachner; Eugene O Apostolov; Alexie G Basnakian; Sudhir Shah; Jacqueline Tilak; Peter A McCullough
Journal:  Cardiorenal Med       Date:  2013-02-06       Impact factor: 2.041

4.  Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study.

Authors:  Anja Haase-Fielitz; Peter R Mertens; Michael Plass; Hermann Kuppe; Roland Hetzer; Mark Westerman; Vaughn Ostland; John R Prowle; Rinaldo Bellomo; Michael Haase
Journal:  Crit Care       Date:  2011-08-04       Impact factor: 9.097

5.  Iron as the key modulator of hepcidin expression in erythroid antibody-mediated hypoplasia.

Authors:  J C Fernandes; P Garrido; S Ribeiro; P Rocha-Pereira; E Bronze-da-Rocha; L Belo; E Costa; F Reis; A Santos-Silva
Journal:  Biomed Res Int       Date:  2014-12-18       Impact factor: 3.411

6.  Assessing the Association between Serum Ferritin, Transferrin Saturation, and C-Reactive Protein in Northern Territory Indigenous Australian Patients with High Serum Ferritin on Maintenance Haemodialysis.

Authors:  Sandawana William Majoni; Paul D Lawton; Federica Barzi; Alan Cass; Jaquelyne T Hughes
Journal:  Int J Nephrol       Date:  2017-01-24
  6 in total

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