| Literature DB >> 19364648 |
Lijun Fan1, Ryan W Lewis, George P Hess, Bruce Ganem.
Abstract
A short and convergent synthetic approach to new photoactivatable precursors of gamma-aminobutyric acid (GABA) is described. When photolyzed, the 'caged' GABA precursor efficiently releases GABA, as judged by depolarization measurements on the mammalian GABA(A) receptor.Entities:
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Year: 2009 PMID: 19364648 DOI: 10.1016/j.bmcl.2009.03.065
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823