D W Stovall1, R B Shabanowitz. 1. Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill.
Abstract
OBJECTIVE: To study the effects of human prolactin (PRL) on human sperm capacitation and acrosome reaction. DESIGN: Acrosome reactions were induced by the addition of follicular fluid (FF) and progesterone (P). Experiments were performed to determine time and dose-dependent effects of PRL on sperm capacitation, potentiation of the acrosome reaction, decapacitating effects, and potential for PRL to induce an acrosome reaction. RESULTS: An average of 31.5% of spermatozoa underwent acrosome reaction with addition of FF and P. No time- or dose-dependent PRL effects on sperm capacitation or acrosome reaction were found (P greater than 0.05). CONCLUSION: Prolactin does not play an important role in human sperm capacitation or acrosome reaction.
OBJECTIVE: To study the effects of humanprolactin (PRL) on human sperm capacitation and acrosome reaction. DESIGN: Acrosome reactions were induced by the addition of follicular fluid (FF) and progesterone (P). Experiments were performed to determine time and dose-dependent effects of PRL on sperm capacitation, potentiation of the acrosome reaction, decapacitating effects, and potential for PRL to induce an acrosome reaction. RESULTS: An average of 31.5% of spermatozoa underwent acrosome reaction with addition of FF and P. No time- or dose-dependent PRL effects on sperm capacitation or acrosome reaction were found (P greater than 0.05). CONCLUSION:Prolactin does not play an important role in human sperm capacitation or acrosome reaction.
Authors: I A Luthy; E Mormandi; S Aszpis; S M Vázquez; G Maccallini; O Levalle; R S Calandra Journal: J Endocrinol Invest Date: 1997-12 Impact factor: 4.256