Literature DB >> 19362883

Prophylactic effect of administration of human gamma globulins in a mouse model of tuberculosis.

Nesty Olivares1, Alina Puig, Diana Aguilar, Aniel Moya, Armando Cádiz, Oscar Otero, Luis Izquierdo, Gustavo Falero, Rosa L Solis, Hector Orozco, Maria E Sarmiento, Mohd Nor Norazmi, Rogelio Hernández-Pando, Armando Acosta.   

Abstract

The protective effect of human gamma globulins on Mycobacterium tuberculosis infection was evaluated in a mouse model of intratracheal infection. Animals receiving human gamma globulins intranasally, 2h before intratracheal challenge showed a significant decrease in lung bacilli load compared to non-treated animals in different time intervals of up to 2 months after challenge. The same effect was obtained when M. tuberculosis was pre-incubated with the gamma globulin before challenge. The protective effect of the gamma-globulin formulation was abolished after pre-incubation with M. tuberculosis. These results suggest a potential role of specific antibodies in the defence against mycobacterial infections.

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Year:  2009        PMID： 19362883     DOI： 10.1016/j.tube.2009.02.003

Source DB:  PubMed          Journal:  Tuberculosis (Edinb)        ISSN： 1472-9792            Impact factor:   3.131


  14 in total

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2.  A novel human IgA monoclonal antibody protects against tuberculosis.

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3.  Second international congress on immunopharmacology: delivery systems and current strategies for drug design.

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Review 4.  Cellular and humoral mechanisms involved in the control of tuberculosis.

Authors:  Joaquin Zuñiga; Diana Torres-García; Teresa Santos-Mendoza; Tatiana S Rodriguez-Reyna; Julio Granados; Edmond J Yunis
Journal:  Clin Dev Immunol       Date:  2012-05-17

Review 5.  Function and Potentials of M. tuberculosis Epitopes.

Authors:  Juraj Ivanyi
Journal:  Front Immunol       Date:  2014-03-24       Impact factor: 7.561

6.  Protective effect of a lipid-based preparation from Mycobacterium smegmatis in a murine model of progressive pulmonary tuberculosis.

Authors:  Maria de los Angeles García; Reinier Borrero; Maria E Lanio; Yanely Tirado; Nadine Alvarez; Alina Puig; Alicia Aguilar; Liem Canet; Dulce Mata Espinoza; Jorge Barrios Payán; María Elena Sarmiento; Rogelio Hernández-Pando; Mohd-Nor Norazmi; Armando Acosta
Journal:  Biomed Res Int       Date:  2014-12-07       Impact factor: 3.411

7.  Cellular Architecture of Spinal Granulomas and the Immunological Response in Tuberculosis Patients Coinfected with HIV.

Authors:  Debapriya Bhattacharya; Siva Danaviah; Daniel M Muema; Ngomu Akeem Akilimali; Prashini Moodley; Thumbi Ndung'u; Gobardhan Das
Journal:  Front Immunol       Date:  2017-09-11       Impact factor: 7.561

8.  Immunogenicity of recombinant Mycobacterium bovis bacille Calmette-Guèrin clones expressing T and B cell epitopes of Mycobacterium tuberculosis antigens.

Authors:  Rohimah Mohamud; Maryam Azlan; Daniel Yero; Nadine Alvarez; Maria E Sarmiento; Armando Acosta; Mohd-Nor Norazmi
Journal:  BMC Immunol       Date:  2013-02-25       Impact factor: 3.615

9.  Passive administration of purified secretory IgA from human colostrum induces protection against Mycobacterium tuberculosis in a murine model of progressive pulmonary infection.

Authors:  Nadine Alvarez; Oscar Otero; Frank Camacho; Reinier Borrero; Yanely Tirado; Alina Puig; Alicia Aguilar; Cesar Rivas; Axel Cervantes; Gustavo Falero-Díaz; Armando Cádiz; María E Sarmiento; Mohd Nor Norazmi; Rogelio Hernández-Pando; Armando Acosta
Journal:  BMC Immunol       Date:  2013-02-25       Impact factor: 3.615

10.  Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas.

Authors:  Alvaro A Ordonez; Supriya Pokkali; Sunhwa Kim; Brian Carr; Mariah H Klunk; Leah Tong; Vikram Saini; Yong S Chang; Matthew McKevitt; Victoria Smith; David L Gossage; Sanjay K Jain
Journal:  PLoS One       Date:  2018-05-14       Impact factor: 3.240
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