OBJECTIVES: The aim of this study was to describe the clinical characteristics of childhood intussusception and to estimate the incidence rate of intussusception before the introduction of rotavirus vaccines in Korea. METHODS: Demographic, clinical, diagnostic, treatment, and outcome data for patients aged <5 years who were diagnosed with intussusception in Jeonbuk Province, South Korea from January 2000 through December 2002, were retrospectively collected using a standardized data collection instrument. RESULTS: During the 3-year period, 408 patients were diagnosed with intussusception; 82.8% of children were aged <24 months. Predominant signs and symptoms were vomiting (64.5%), bloody stool (43.9%), and abdominal pain/irritability (41.9%). The combination of ultrasound and barium or air enema was the most frequently used diagnostic approach (38.7%). Three hundred and thirteen patients (76.7%) were treated by radiologic reduction, 88 (21.6%) patients were treated by surgical intervention, and the remaining seven patients had no treatment. The mean annual incidence rate of intussusception in Jeonbuk Province was 236/100,000 among children aged <2 years and 106/100,000 among children aged <5 years. CONCLUSIONS: This retrospective study provides a background incidence rate of childhood intussusception in Korean children before the introduction of the rotavirus vaccine.
OBJECTIVES: The aim of this study was to describe the clinical characteristics of childhood intussusception and to estimate the incidence rate of intussusception before the introduction of rotavirus vaccines in Korea. METHODS: Demographic, clinical, diagnostic, treatment, and outcome data for patients aged <5 years who were diagnosed with intussusception in Jeonbuk Province, South Korea from January 2000 through December 2002, were retrospectively collected using a standardized data collection instrument. RESULTS: During the 3-year period, 408 patients were diagnosed with intussusception; 82.8% of children were aged <24 months. Predominant signs and symptoms were vomiting (64.5%), bloody stool (43.9%), and abdominal pain/irritability (41.9%). The combination of ultrasound and barium or air enema was the most frequently used diagnostic approach (38.7%). Three hundred and thirteen patients (76.7%) were treated by radiologic reduction, 88 (21.6%) patients were treated by surgical intervention, and the remaining seven patients had no treatment. The mean annual incidence rate of intussusception in Jeonbuk Province was 236/100,000 among children aged <2 years and 106/100,000 among children aged <5 years. CONCLUSIONS: This retrospective study provides a background incidence rate of childhood intussusception in Korean children before the introduction of the rotavirus vaccine.
Authors: Steven Hawken; Robin Ducharme; Laura C Rosella; Eric I Benchimol; Joanne M Langley; Kumanan Wilson; Natasha S Crowcroft; Scott A Halperin; Shalina Desai; Monika Naus; Carolyn J Sanford; Salah M Mahmud; Shelley L Deeks Journal: Hum Vaccin Immunother Date: 2016-11-11 Impact factor: 3.452
Authors: Syed M Satter; Negar Aliabadi; Catherine Yen; Paul A Gastañaduy; Makhdum Ahmed; Abdullah Mamun; Khaleda Islam; Meerjady S Flora; Mahmudur Rahman; K Zaman; Mustafizur Rahman; James D Heffelfinger; Stephen P Luby; Emily S Gurley; Umesh D Parashar Journal: Vaccine Date: 2017-09-20 Impact factor: 3.641
Authors: Soojin Jo; In Seok Lim; Soo Ahn Chae; Sin Weon Yun; Na Mi Lee; Su Yeong Kim; Dae Yong Yi Journal: BMC Pediatr Date: 2019-06-28 Impact factor: 2.125
Authors: Soyun Hwang; Joonghee Kim; Jae Yun Jung; Eun Mi Ham; Joong Wan Park; Hyuksool Kwon; Do Kyun Kim; Young Ho Kwak Journal: PLoS One Date: 2019-12-20 Impact factor: 3.240