Literature DB >> 19362472

An enantioselective synthesis of (+)-(S)-[n]-gingerols via the L-proline-catalyzed aldol reaction.

Shichao Ma1, Shilei Zhang, Wenhu Duan, Wei Wang.   

Abstract

An enantioselective approach to (+)-(S)-[n]-gingerols (1a-c) has been developed. The requisite stereogenic centers of target molecules are facilely constructed by the proline-catalyzed cross-aldol reaction from readily available achiral starting materials.

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Year:  2009        PMID: 19362472     DOI: 10.1016/j.bmcl.2009.03.081

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Gingerol protects against experimental liver fibrosis in rats via suppression of pro-inflammatory and profibrogenic mediators.

Authors:  Mardi M Algandaby; Ali M El-Halawany; Hossam M Abdallah; Abdulrahman M Alahdal; Ayman A Nagy; Osama M Ashour; Ashraf B Abdel-Naim
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-01-26       Impact factor: 3.000

2.  Phenolics Isolated from Aframomum meleguta Enhance Proliferation and Ossification Markers in Bone Cells.

Authors:  Ashraf B Abdel-Naim; Abdullah A Alghamdi; Mardi M Algandaby; Fahad A Al-Abbasi; Ahmed M Al-Abd; Hossam M Abdallah; Ali M El-Halawany; Masao Hattori
Journal:  Molecules       Date:  2017-09-04       Impact factor: 4.411

  2 in total

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