Literature DB >> 1936185

Radio-isotopic determination of hydrogen peroxide in aqueous humor and urine.

S Ramachandran1, S M Morris, P Devamanoharan, M Henein, S D Varma.   

Abstract

The concentrations of hydrogen peroxide in the aqueous humor and urine of several animal species and humans have been determined. The determinations are based on peroxide-dependent decarboxylation of I-[14C]-alpha-ketoglutaric acid and measurement of the resulting 14CO2 by quantitating the radioactive disintegration. The levels of H2O2 in most animals varied between 5.0 and 41 microM for aqueous, and 115 and 187 microM for urine. The levels of peroxide in the urine of steer, cat and baboon were lower and fell out of the above range. In the aqueous of humans with cataracts, the levels ranged from 33 to 324 microM, the overall average being 189 +/- 88 microM. The source of such high levels in the aqueous of cataract patients is currently being studied.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1936185     DOI： 10.1016/0014-4835(91)90167-d

Source DB:  PubMed          Journal:  Exp Eye Res        ISSN： 0014-4835            Impact factor:   3.467


  11 in total

Review 1.  Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration.

Authors:  Fu Shang; Allen Taylor
Journal:  Mol Aspects Med       Date:  2012-04-10

2.  Effect of inhibition of cyclooxygenase on pre- and postjunctional actions of peroxides in the iris-ciliary body.

Authors:  J Graham; S O Awe; A M LeDay; J C Rice; G Ramos; L C Harris; C A Opere; S E Ohia
Journal:  Neurochem Res       Date:  2000-04       Impact factor: 3.996

Review 3.  Obesity and eye diseases.

Authors:  Ning Cheung; Tien Y Wong
Journal:  Surv Ophthalmol       Date:  2007 Mar-Apr       Impact factor: 6.048

4.  Concentration dependent effects of hydrogen peroxide on lens epithelial cells.

Authors:  N Ohguro; M Fukuda; T Sasabe; Y Tano
Journal:  Br J Ophthalmol       Date:  1999-09       Impact factor: 4.638

5.  Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures.

Authors:  Jamie Hsiung; Danhong Zhu; David R Hinton
Journal:  Stem Cells Transl Med       Date:  2014-11-19       Impact factor: 6.940

6.  Photochemically induced cataracts in rat lenses can be prevented by AL-3823A, a glutathione peroxidase mimic.

Authors:  A Spector; G M Wang; R R Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

7.  Effects of 17β-estradiol on proliferation, cell viability and intracellular redox status in native human lens epithelial cells.

Authors:  D Celojevic; A Petersen; J-O Karlsson; A Behndig; M Zetterberg
Journal:  Mol Vis       Date:  2011-07-20       Impact factor: 2.367

8.  Lutein and zeaxanthin supplementation reduces H2O2-induced oxidative damage in human lens epithelial cells.

Authors:  Shasha Gao; Tingyu Qin; Zhenzhen Liu; Maria Andrea Caceres; Carlos F Ronchi; C-Y Oliver Chen; Kyung-Jin Yeum; Allen Taylor; Jeffery B Blumberg; Yizhi Liu; Fu Shang
Journal:  Mol Vis       Date:  2011-12-07       Impact factor: 2.367

9.  Protective effects of epigallocatechin gallate after UV irradiation of cultured human lens epithelial cells.

Authors:  Jun Heo; Byung Rae Lee; Jae Woong Koh
Journal:  Korean J Ophthalmol       Date:  2008-09

10.  Lens aquaporins function as peroxiporins to facilitate membrane transport of hydrogen peroxide.

Authors:  Kulandaiappan Varadaraj; S Sindhu Kumari
Journal:  Biochem Biophys Res Commun       Date:  2020-02-13       Impact factor: 3.322
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.