| Literature DB >> 19361202 |
Yuta Tsunematsu1, Osamu Ohno, Kaori Konishi, Kaoru Yamada, Masami Suganuma, Daisuke Uemura.
Abstract
Symbiospirols A, B, and C, long carbon-chain compounds with a molecular weight of 1207 were isolated from the cultured symbiotic dinoflagellate Symbiodinium sp. Their planar structures and partial relative stereochemistries were elucidated based on 1D and 2D NMR spectra and a degradation reaction. Symbiospirols consisted of a C67-linear chain with a beta,beta'-dihydroxyl ketone moiety, eight hydroxyl groups, one tetrahydropyran ring, and two 1,6-dioxaspiro[4,4]nonane rings. Symbiospirol A had an inhibitory effect against l-phosphatidylserine-induced PKC activation.Entities:
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Year: 2009 PMID： 19361202 DOI： 10.1021/ol900299x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005