| Literature DB >> 19361186 |
Yong-Shou Tian1, Jae-Eun Joo, Bae-Soo Kong, Van-Thoai Pham, Kee-Young Lee, Won-Hun Ham.
Abstract
We report a new asymmetric synthetic method for (-)-swainsonine utilizing a chiral oxazoline precursor. The key features in this strategy are the diastereoselective oxazoline formation reaction catalyzed by palladium(0), diasteroselective dihydroxylation, and the stereocontrolled allylation reaction with TiCl(4).Entities:
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Year: 2009 PMID： 19361186 DOI： 10.1021/jo802800d
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354