Literature DB >> 19361162

DNA condensation induced by ruthenium(II) polypyridyl complexes [Ru(bpy)(2)(PIPSH)](2+) and [Ru(bpy)(2)(PIPNH)](2+).

Bin Sun1, Jing-Xin Guan, Li Xu, Bo-Le Yu, Long Jiang, Jun-Feng Kou, Li Wang, Xi-Dong Ding, Hui Chao, Liang-Nian Ji.   

Abstract

Two novel DNA-intercalating ruthenium(II) complexes, [Ru(bpy)(2)(PIPSH)](2+) and [Ru(bpy)(2)(PIPNH)](2+), have been synthesized and characterized. Gel retardation assay, atomic force microscopy, and dynamic light scattering studies show that both complexes can induce the condensation of originally circular plasmid pBR322 DNA to particulate structures under neutral conditions.

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Year:  2009        PMID: 19361162     DOI: 10.1021/ic900102r

Source DB:  PubMed          Journal:  Inorg Chem        ISSN: 0020-1669            Impact factor:   5.165


  6 in total

1.  First ruthenium organometallic complex of antibacterial agent ofloxacin. Crystal structure and interactions with DNA.

Authors:  Iztok Turel; Jakob Kljun; Franc Perdih; Elena Morozova; Vladimir Bakulev; Nina Kasyanenko; Jo Ann W Byl; Neil Osheroff
Journal:  Inorg Chem       Date:  2010-10-26       Impact factor: 5.165

2.  Synthesis, characterization, and DNA binding, photocleavage, cytotoxicity, cellular uptake, apoptosis, and on-off light switching studies of Ru(II) mixed-ligand complexes containing 7-fluorodipyrido[3,2-a:2',3'-c]phenazine.

Authors:  Nancherla Deepika; Yata Praveen Kumar; Chittimalli Shobha Devi; Putta Venkat Reddy; Avudoddi Srishailam; Sirasani Satyanarayana
Journal:  J Biol Inorg Chem       Date:  2013-07-12       Impact factor: 3.358

3.  Self-assembly of c-myc DNA promoted by a single enantiomer ruthenium complex as a potential nuclear targeting gene carrier.

Authors:  Qiong Wu; Wenjie Mei; Kangdi Zheng; Yang Ding
Journal:  Sci Rep       Date:  2016-07-06       Impact factor: 4.379

4.  A Simple Zn2+ Complex-Based Composite System for Efficient Gene Delivery.

Authors:  Zhe Zhang; Yanjie Zhao; Xianggao Meng; Dan Zhao; Dan Zhang; Li Wang; Changlin Liu
Journal:  PLoS One       Date:  2016-07-19       Impact factor: 3.240

5.  Mitochondria Targeted Protein-Ruthenium Photosensitizer for Efficient Photodynamic Applications.

Authors:  Sabyasachi Chakrabortty; Bikram Keshari Agrawalla; Anne Stumper; Naidu M Vegi; Stephan Fischer; Christian Reichardt; Michael Kögler; Benjamin Dietzek; Michaela Feuring-Buske; Christian Buske; Sven Rau; Tanja Weil
Journal:  J Am Chem Soc       Date:  2017-02-07       Impact factor: 15.419

6.  N,N-Di-phenyl-4-(1H-pyrrolo[1,2-f][1,10]phenanthro-lin-2-yl)-aniline ethanol monosolvate.

Authors:  Jun-Shan Luo; Yan-Yan Zhang; Zhao-Di Liu; Yu-Peng Tian
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-04-10
  6 in total

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