| Literature DB >> 19361162 |
Bin Sun1, Jing-Xin Guan, Li Xu, Bo-Le Yu, Long Jiang, Jun-Feng Kou, Li Wang, Xi-Dong Ding, Hui Chao, Liang-Nian Ji.
Abstract
Two novel DNA-intercalating ruthenium(II) complexes, [Ru(bpy)(2)(PIPSH)](2+) and [Ru(bpy)(2)(PIPNH)](2+), have been synthesized and characterized. Gel retardation assay, atomic force microscopy, and dynamic light scattering studies show that both complexes can induce the condensation of originally circular plasmid pBR322 DNA to particulate structures under neutral conditions.Entities:
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Year: 2009 PMID: 19361162 DOI: 10.1021/ic900102r
Source DB: PubMed Journal: Inorg Chem ISSN: 0020-1669 Impact factor: 5.165