Literature DB >> 19360421

Spinal epidural hematoma in hemophilic children: controversies in management.

Pilar Varela Rois1, Manuel Rodríguez López, Beatriz Cabanas López de Vergara, Adolfo de la Lama Zaragoza, Jesús González García, Jorge Mañas Uxo.   

Abstract

INTRODUCTION AND
OBJECTIVE: Spinal epidural hematoma (SEH) is an uncommon complication in hemophilic children. It can produce rapidly progressive neurological deficits. We aim to discuss the different management options for these patients. CASE REPORT: A 13-year-old boy with a history of hemophilia A was admitted with acute onset of localized spine pain and weakness. No trauma was reported on review of the history. Recombinant factor VIII aggressive replacement therapy was started. Spinal magnetic resonance imaging revealed an extradural mass lesion extending from D5 to D6 level. Emergency hemilaminectomies of D5 and D6 and evacuation of the clot were done. The patient made excellent recovery following surgery.
CONCLUSION: Early diagnosis and immediate aggressive replacement therapy are mandatory in the management of SEH. Prompt surgical decompression to avoid any permanent neurological deficit is a safe and effective treatment option for an SEH in selected hemophilic children.

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Year:  2009        PMID: 19360421     DOI: 10.1007/s00381-009-0861-3

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  16 in total

1.  Experience in the surgical management of spontaneous spinal epidural hematoma.

Authors:  Cheng-Chih Liao; Shih-Tseng Lee; Wen-Chin Hsu; Li-Rong Chen; Tai-Ngar Lui; Sai-Cheung Lee
Journal:  J Neurosurg       Date:  2004-01       Impact factor: 5.115

Review 2.  Literature review of surgery management in inhibitor patients.

Authors:  E C Rodriguez-Merchan; A Rocino
Journal:  Haemophilia       Date:  2004-09       Impact factor: 4.287

3.  Conservative treatment of spontaneous spinal epidural hematoma associated with oral anticoagulant therapy in a child.

Authors:  Jignesh Tailor; Ian F Dunn; Edward Smith
Journal:  Childs Nerv Syst       Date:  2006-09-15       Impact factor: 1.475

4.  Spinal hematoma unrelated to previous surgery: analysis of 15 consecutive cases treated in a single institution within a 10-year period.

Authors:  Wolfgang Börm; Klaus Mohr; Uwe Hassepass; Hans-Peter Richter; Erich Kast
Journal:  Spine (Phila Pa 1976)       Date:  2004-12-15       Impact factor: 3.468

5.  Spinal epidural haematoma in a patient with haemophilia B.

Authors:  C Balkan; K Kavakli; D Karapinar
Journal:  Haemophilia       Date:  2006-07       Impact factor: 4.287

6.  Spontaneous spinal epidural hematoma: an uncommon presentation of a rare disease.

Authors:  Sarit Ravid; Steven Schneider; Joseph Maytal
Journal:  Childs Nerv Syst       Date:  2002-01-22       Impact factor: 1.475

7.  Successful surgical treatment of a hemophiliac infant with nontraumatic acute subdural hematoma.

Authors:  Naci Balak; Gōkalp Silav; Yilmaz Kiliç; Cetin Timur; Ilhan Elmaci
Journal:  Surg Neurol       Date:  2007-11

Review 8.  Spinal hematoma: a literature survey with meta-analysis of 613 patients.

Authors:  D Kreppel; G Antoniadis; W Seeling
Journal:  Neurosurg Rev       Date:  2002-09-24       Impact factor: 3.042

9.  Spinal epidural hematoma in an infant as the initial presentation of severe hemophilia.

Authors:  Peter Kalina; Jonathan Morris; Corey Raffel
Journal:  Emerg Radiol       Date:  2007-09-18

10.  Spinal subdural hematoma revealing hemophilia A in a child: A case report.

Authors:  Behzad Eftekhar; Mohammad Ghodsi; Ebrahim Ketabchi; Abbas Bakhtiari; Pardis Mostajabi
Journal:  BMC Blood Disord       Date:  2003-08-07
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  6 in total

1.  [Spinal epidural hematoma].

Authors:  P Papanagiotou
Journal:  Radiologe       Date:  2012-05       Impact factor: 0.635

2.  Spinal epidural hematoma in a patient with hemophilia B presenting as acute abdomen.

Authors:  Nilay Nirupam; Harish Pemde; Jagdish Chandra
Journal:  Indian J Hematol Blood Transfus       Date:  2013-03-07       Impact factor: 0.900

3.  Haemophilia A presenting as spontaneous spinal epidural haematoma in a 3-month-old infant.

Authors:  Narendra Rathi; Akanksha Rathi
Journal:  BMJ Case Rep       Date:  2010-10-21

4.  Epidural Hematoma Related with Low-Dose Aspirin : Complete Recovery without Surgical Treatment.

Authors:  Kyoung-Tae Kim; Dae-Chul Cho; Suk-Won Ahn; Suk-Hyung Kang
Journal:  J Korean Neurosurg Soc       Date:  2012-05-31

5.  Full-endoscopic interlaminar removal of chronic lumbar epidural hematoma after spinal manipulation.

Authors:  Yen-Po Cheng; Kwo-Whei Lee; Ping-Yi Lin; Abel Po-Hao Huang; Chun-Yuan Cheng; Hsin-I Ma; Chien-Min Chen; Dueng-Yuan Hueng
Journal:  Surg Neurol Int       Date:  2014-04-19

6.  Spontaneous Spinal Epidural Haematoma Secondary to Autoimmune Acquired Haemophilia.

Authors:  Fardad T Afshari; Dhruv Parikh; Vladimir Petrik
Journal:  Case Rep Neurol       Date:  2018-12-13
  6 in total

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