BACKGROUND: The extent to which chronic exposure to outdoor air pollutants influences lung function in adults is unclear. The aim of this study was to measure the association between chronic exposure to outdoor air pollutants and adult lung function. METHODS: The relationship between measures of lung function (forced expiratory volume in 1 s (FEV(1)) and FEV(1) as a percentage of forced vital capacity (FVC)) and average exposure to particulate matter <10 microm in diameter, nitrogen dioxide, sulfur dioxide and ozone was examined in four representative cross-sectional surveys of the English population aged > or =16 in 1995, 1996, 1997 and 2001. Year-specific estimates were pooled using fixed effects meta-analysis. RESULTS: Greater exposure to particulate matter <10 microm in diameter, nitrogen dioxide and sulfur dioxide was associated with lower adult FEV(1). The size of the effect on population mean FEV(1) was about 3% for particulate matter <10 microm, and 0.7% for nitrogen dioxide and sulfur dioxide, for a 10 microg/m(3) increase in pollutant concentration. The effects were most marked in men, older adults and ex-smokers. FEV(1) was not associated with ozone concentration. No associations were found between the pollutants and FEV(1) as a percentage of FVC. CONCLUSIONS: Chronic exposure to outdoor air pollution is associated with modestly reduced FEV(1) in adults.
BACKGROUND: The extent to which chronic exposure to outdoor air pollutants influences lung function in adults is unclear. The aim of this study was to measure the association between chronic exposure to outdoor air pollutants and adult lung function. METHODS: The relationship between measures of lung function (forced expiratory volume in 1 s (FEV(1)) and FEV(1) as a percentage of forced vital capacity (FVC)) and average exposure to particulate matter <10 microm in diameter, nitrogen dioxide, sulfur dioxide and ozone was examined in four representative cross-sectional surveys of the English population aged > or =16 in 1995, 1996, 1997 and 2001. Year-specific estimates were pooled using fixed effects meta-analysis. RESULTS: Greater exposure to particulate matter <10 microm in diameter, nitrogen dioxide and sulfur dioxide was associated with lower adult FEV(1). The size of the effect on population mean FEV(1) was about 3% for particulate matter <10 microm, and 0.7% for nitrogen dioxide and sulfur dioxide, for a 10 microg/m(3) increase in pollutant concentration. The effects were most marked in men, older adults and ex-smokers. FEV(1) was not associated with ozone concentration. No associations were found between the pollutants and FEV(1) as a percentage of FVC. CONCLUSIONS: Chronic exposure to outdoor air pollution is associated with modestly reduced FEV(1) in adults.
Authors: Mary B Rice; Petter L Ljungman; Elissa H Wilker; Kirsten S Dorans; Diane R Gold; Joel Schwartz; Petros Koutrakis; George R Washko; George T O'Connor; Murray A Mittleman Journal: Am J Respir Crit Care Med Date: 2015-03-15 Impact factor: 21.405
Authors: Sandrah P Eckel; Thomas A Louis; Paulo H M Chaves; Linda P Fried; And Helene G Margolis Journal: Am J Epidemiol Date: 2012-07-18 Impact factor: 4.897
Authors: Robert Urman; Erika Garcia; Kiros Berhane; Rob McConnell; W James Gauderman; Frank Gilliland Journal: Am J Respir Crit Care Med Date: 2020-02-15 Impact factor: 21.405
Authors: Jamie Rylance; Stephen B Gordon; Luke P Naeher; Archana Patel; John R Balmes; Olorunfemi Adetona; Derek K Rogalsky; William J Martin Journal: Am J Physiol Lung Cell Mol Physiol Date: 2013-03-01 Impact factor: 5.464
Authors: Daniela Nuvolone; Roberto Della Maggiore; Sara Maio; Roberto Fresco; Sandra Baldacci; Laura Carrozzi; Francesco Pistelli; Giovanni Viegi Journal: Environ Health Date: 2011-03-01 Impact factor: 5.984
Authors: Mary B Rice; Wenyuan Li; Kirsten S Dorans; Elissa H Wilker; Petter Ljungman; Diane R Gold; Joel Schwartz; Petros Koutrakis; Itai Kloog; Tetsuro Araki; Hiroto Hatabu; Raul San Jose Estepar; George T O'Connor; Murray A Mittleman; George R Washko Journal: Epidemiology Date: 2018-05 Impact factor: 4.822