Literature DB >> 19358375

Genetic sensitivity to 6-n-propylthiouracil (PROP) as a screening tool for obesity and dental caries in children.

Amitha M Hedge1, Akhilesh Sharma.   

Abstract

PURPOSE: Dental caries and childhood obesity epidemics are multifactorial complex disease and children's dietary pattern is a common underlying etiologic factor in their causation. Dietary preferences and taste are genetically determined. In the present study children were identified who are at greater risk for developing dental caries and obesity so as to institute preventive measures at an early stage. MATERIALS: Among 500 children belonging to the age group of 8-12 years of both sexes PROP sensitivity test was carried out. Body mass index was determined and the caries experience was recorded. A Questionnaire was prepared and given to the parents of the children to evaluate their dietary habits. The results were subjected to statistical analysis using prevalence test, ANOVA test and chi-square test.
RESULTS: We found that the non taster children had higher caries experience and body weight respectively as compared to children who were super-tasters and medium tasters. Super-tasters tended to be sweet and fatty food dislikers and non-tasters tended to be likers.
CONCLUSIONS: The PROP test proved to be a useful tool in determining the genetic sensitivity levels of the bitter taste and could be used as a useful screening tool to identify children at risk of developing obesity and dental caries.

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Year:  2008        PMID: 19358375

Source DB:  PubMed          Journal:  J Clin Pediatr Dent        ISSN: 1053-4628            Impact factor:   1.065


  5 in total

1.  Role of taste perception in white spot lesion formation during orthodontic treatment.

Authors:  Abrar Alanzi; Marianna Velissariou; Manal Abu Al-Melh; Donald Ferguson; Katerina Kavvadia
Journal:  Angle Orthod       Date:  2019-03-06       Impact factor: 2.079

2.  Association of Mothers' Genetic Taste Perception to Eating Habits and Its Influence on Early Childhood Caries in Preschool Children: An Analytical Study.

Authors:  Krithi Nellamakkada; Sandya S Patil; Madhu Kakanur; Ravi S Kumar; Rachna Thakur
Journal:  Int J Clin Pediatr Dent       Date:  2022

3.  Caries risk in children of Udaipur City, India using genetic taste sensitivity to 6-n-propylthiouracil.

Authors:  Payel Karmakar; Ruchi Arora; Chhaya Patel; Bhumi Sarvaiya; Aditi Singh; Mittal Patel
Journal:  J Int Soc Prev Community Dent       Date:  2016 Nov-Dec

4.  Correlation of Mother and Child's Taste Perception and their Caries Experience.

Authors:  K Abhiram; A J Sai Sankar; E Sridevi; M Sridhar; K Pranitha; D Aruna
Journal:  Contemp Clin Dent       Date:  2019 Jul-Sep

5.  Association between genetic taste sensitivity, 2D:4D ratio, dental caries prevalence, and salivary flow rate in 6-14-year-old children: a cross-sectional study.

Authors:  Chintamaneni Raja Lakshmi; Doppalapudi Radhika; Mpv Prabhat; Sujana Mulk Bhavana; Nallamilli Sai Madhavi
Journal:  J Dent Res Dent Clin Dent Prospects       Date:  2016-08-17
  5 in total

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