Literature DB >> 19355803

The total economic burden of overactive bladder in the United States: a disease-specific approach.

Ebere Onukwugha1, Ilene H Zuckerman, Diane McNally, Karin S Coyne, Vasudha Vats, C Daniel Mullins.   

Abstract

OBJECTIVE: To employ results from a recent US population-based survey to calculate disease-specific total costs of overactive bladder (OAB). STUDY
DESIGN: Disease-specific total cost-of-illness method using population prevalence estimates.
METHODS: Cases were identified as community-dwelling adults reporting the presence of urinary urgency or urgency urinary incontinence. Two OAB classifications were used based on Likert scale responses of OAB symptoms: "often" (base case) or "sometimes" (alternative). The study estimates disease-specific total costs of OAB from the societal perspective and using an average costing method. A population-based survey, a claims data analysis, and the published literature provided the prevalence and resource utilization data.
RESULTS: The prevalence of OAB as defined in the base case (alternative) was 18.6% (28.7%) in the adult US population, accounting for 42.2 million (65.1 million) community-dwelling adults. The disease-specific total cost of OAB is estimated at $24.9 billion for the base case and $36.5 billion for the alternative case. Total direct costs were $22.3 billion in the base case and $33.5 billion in the alternative case. Costs were higher among adults younger than 65 years of age, compared with adults 65 years or older. This relative cost burden was lower for the base case compared with the alternative case in the full sample, with a larger gap among men.
CONCLUSION: The total cost of OAB among community-dwelling adults is significant and varies with demographic groups. Future research is needed to determine whether the differential cost burden is robust to alternate cost-of-illness estimation methods.

Entities:  

Mesh:

Year:  2009        PMID: 19355803

Source DB:  PubMed          Journal:  Am J Manag Care        ISSN: 1088-0224            Impact factor:   2.229


  35 in total

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Authors:  Douglas G Tincello
Journal:  World J Urol       Date:  2011-10-15       Impact factor: 4.226

2.  Time-to-effect with darifenacin in overactive bladder: a pooled analysis.

Authors:  Vik Khullar; Jenelle Foote; Yodit Seifu; Mathias Egermark
Journal:  Int Urogynecol J       Date:  2011-10-18       Impact factor: 2.894

3.  Novel insights into development of diabetic bladder disorder provided by metabolomic analysis of the rat nondiabetic and diabetic detrusor and urothelial layer.

Authors:  Yi Wang; Gary G Deng; Kelvin P Davies
Journal:  Am J Physiol Endocrinol Metab       Date:  2016-06-28       Impact factor: 4.310

Review 4.  Patient-reported outcomes and different approaches to urinary parameters in overactive bladder: what should we measure?

Authors:  Vik Khullar
Journal:  Int Urogynecol J       Date:  2011-10-20       Impact factor: 2.894

5.  The Burden of Overactive Bladder on US Public Health.

Authors:  W Stuart Reynolds; Jay Fowke; Roger Dmochowski
Journal:  Curr Bladder Dysfunct Rep       Date:  2016-01-23

6.  Overactive bladder in men: a practical approach.

Authors:  Alexandra L Millman; Douglas C Cheung; Cian Hackett; Dean Elterman
Journal:  Br J Gen Pract       Date:  2018-06       Impact factor: 5.386

7.  Urge incontinence: estimating environmental and obstetrical risk factors using an identical twin study.

Authors:  Tondalaya L Gamble; Hongyan Du; Peter K Sand; Sylvia M Botros; Magdalena Rurak; Roger P Goldberg
Journal:  Int Urogynecol J       Date:  2010-05-06       Impact factor: 2.894

Review 8.  The effect of onabotulinumtoxinA according to site of injection in patients with overactive bladder: a systematic review and meta-analysis.

Authors:  Jung Ki Jo; Kyu Nam Kim; Dong Won Kim; Yong Tae Kim; Ji Yoon Kim; Ji Yeon Kim
Journal:  World J Urol       Date:  2017-11-09       Impact factor: 4.226

9.  Role of botulinum toxin-A in refractory idiopathic overactive bladder patients without detrusor overactivity.

Authors:  Prashanth Kanagarajah; Rajinikanth Ayyathurai; Daniel J Caruso; Christopher Gomez; Angelo E Gousse
Journal:  Int Urol Nephrol       Date:  2011-06-04       Impact factor: 2.370

10.  The Spectrum of Bladder Health: The Relationship Between Lower Urinary Tract Symptoms and Interference with Activities.

Authors:  Siobhan Sutcliffe; Tamara Bavendam; Charles Cain; C Neill Epperson; Colleen M Fitzgerald; Sheila Gahagan; Alayne D Markland; David A Shoham; Ariana L Smith; Mary K Townsend; Kyle Rudser
Journal:  J Womens Health (Larchmt)       Date:  2019-05-06       Impact factor: 2.681

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