| Literature DB >> 19354231 |
Philip C Bulman Page1, Louise F Appleby, David Day, Yohan Chan, Benjamin R Buckley, Steven M Allin, Michael J McKenzie.
Abstract
Concise highly enantioselective three-step syntheses are described for (-)-(3'S)-lomatin and (+)-(3'S,4'R)-trans-khellactone from 7-hydroxycoumarin in 97% ee and in 57% and 58% overall yields, respectively, using nonaqueous enantioselective epoxidation by an iminium salt as the key step.Entities:
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Year: 2009 PMID： 19354231 DOI： 10.1021/ol900444h
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005