Literature DB >> 19352699

Cutaneous presentation of kwashiorkor due to infantile Crohn's disease.

Luluah Al-Mubarak1, Sultan Al-Khenaizan, Talal Al Goufi.   

Abstract

Kwashiorkor is one of the severe forms of protein-energy malnutrition. Many characteristic dermatoses can be seen in children suffering from kwashiorkor, and some are pathognomonic. Here, we report an infant who presented with diarrhea and skin signs of kwashiorkor, and duodenal biopsy was consistent with Crohn's disease. The patient was treated with prednisolone administered orally in a tapering course plus azathioprine, in addition to nutritional supplementation. The general condition of the patient quickly improved and his skin lesions completely resolved within 2 weeks. Kwashiorkor is a serious potentially fatal disease that occurs less often in developed countries leading to low index of suspicion by physicians and pediatricians in those regions. Occasionally, dermatologists have the rare chance of alerting pediatricians to the diagnosis of kwashiorkor, thus making a difference in the care of this disease.

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Year:  2009        PMID: 19352699     DOI: 10.1007/s00431-009-0981-5

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.860


  10 in total

1.  Prospective survey of childhood inflammatory bowel disease in the British Isles.

Authors:  A Sawczenko; B K Sandhu; R F Logan; H Jenkins; C J Taylor; S Mian; R Lynn
Journal:  Lancet       Date:  2001-04-07       Impact factor: 79.321

2.  The enamel paint sign in the dermatologic diagnosis of early-onset Kwashiorkor.

Authors:  I J Buño; J G Morelli; W L Weston
Journal:  Arch Dermatol       Date:  1998-01

Review 3.  Cutaneous manifestation of internal diseases in infants and children.

Authors:  Marcia Ramos-e-Silva; Flavia Haikal Tanus; Tania Ferreira Cestari
Journal:  Clin Dermatol       Date:  2002 Jan-Feb       Impact factor: 3.541

4.  Short-term prognosis in protein-calorie malnutrition.

Authors:  D S McLaren; E Shirajian; H Loshkajian; S Shadarevian
Journal:  Am J Clin Nutr       Date:  1969-07       Impact factor: 7.045

5.  Skin breakdown in kwashiorkor responds to zinc.

Authors:  M H Golden; B E Golden; A A Jackson
Journal:  Lancet       Date:  1980-06-07       Impact factor: 79.321

Review 6.  The effects of malnutrition in the metabolism of children.

Authors:  M Golden
Journal:  Trans R Soc Trop Med Hyg       Date:  1988       Impact factor: 2.184

Review 7.  Metabolism and functions of highly unsaturated fatty acids: an update.

Authors:  M T Nakamura; H P Cho; J Xu; Z Tang; S D Clarke
Journal:  Lipids       Date:  2001-09       Impact factor: 1.880

8.  Dermatosis in a child with kwashiorkor secondary to food aversion.

Authors:  J P Eastlack; K K Grande; M L Levy; J F Nigro
Journal:  Pediatr Dermatol       Date:  1999 Mar-Apr       Impact factor: 1.588

9.  Essential fatty acid status in paediatric Crohn's disease: relationship with disease activity and nutritional status.

Authors:  T M Trebble; S A Wootton; A May; M D S Erlewyn-Lajeunesse; A Chakraborty; M A Mullee; M A Stroud; R M Beattie
Journal:  Aliment Pharmacol Ther       Date:  2003-08-15       Impact factor: 8.171

Review 10.  Skin in protein energy malnutrition.

Authors:  D S McLaren
Journal:  Arch Dermatol       Date:  1987-12
  10 in total

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