Literature DB >> 19352364

Leveraging biotech's drug discovery expertise for neglected diseases.

Joanna E Lowell1, Christopher D Earl.   

Abstract

Mesh：

Year:  2009        PMID： 19352364     DOI： 10.1038/nbt0409-323

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  19 in total

Review 1.  Drugs for neglected diseases: a failure of the market and a public health failure?

Authors:  P Trouiller; E Torreele; P Olliaro; N White; S Foster; D Wirth; B Pécoul
Journal:  Trop Med Int Health       Date:  2001-11       Impact factor: 2.622

Review 2.  Antimalarial drug discovery: old and new approaches.

Authors:  Philip J Rosenthal
Journal:  J Exp Biol       Date:  2003-11       Impact factor: 3.312

3.  Experiments in social responsibility.

Authors:  Paul Herrling
Journal:  Nature       Date:  2006-01-19       Impact factor: 49.962

4.  Global framework on essential health R&D.

Authors:  Pierre Chirac; Els Torreele
Journal:  Lancet       Date:  2006-05-13       Impact factor: 79.321

5.  Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk.

Authors:  Cassandra L Woodard; Susan M Keenan; Lucia Gerena; William J Welsh; Jeanne A Geyer; Norman C Waters
Journal:  Bioorg Med Chem Lett       Date:  2007-06-12       Impact factor: 2.823

6.  Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin.

Authors:  Tansy C Hammarton; Jade Clark; Fiona Douglas; Michael Boshart; Jeremy C Mottram
Journal:  J Biol Chem       Date:  2003-04-07       Impact factor: 5.157

Review 7.  Protein kinases as drug targets in trypanosomes and Leishmania.

Authors:  Christina Naula; Marilyn Parsons; Jeremy C Mottram
Journal:  Biochim Biophys Acta       Date:  2005-09-08

8.  The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion.

Authors:  Xiaoming Tu; Ching C Wang
Journal:  J Biol Chem       Date:  2004-03-08       Impact factor: 5.157

9.  New drugs for neglected diseases: from pipeline to patients.

Authors:  Bernard Pécoul
Journal:  PLoS Med       Date:  2004-10-19       Impact factor: 11.069

Review 10.  Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote.

Authors:  Pauline Ward; Leila Equinet; Jeremy Packer; Christian Doerig
Journal:  BMC Genomics       Date:  2004-10-12       Impact factor: 3.969
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  1 in total

1.  The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis.

Authors:  Andrew P Jackson; Mandy Sanders; Andrew Berry; Jacqueline McQuillan; Martin A Aslett; Michael A Quail; Bridget Chukualim; Paul Capewell; Annette MacLeod; Sara E Melville; Wendy Gibson; J David Barry; Matthew Berriman; Christiane Hertz-Fowler
Journal:  PLoS Negl Trop Dis       Date:  2010-04-13
  1 in total

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