Tae Yeon Jeon1, Seong Hyun Kim, Won Jae Lee, Hyo K Lim. 1. Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon-dong, Gangnam-gu, Seoul, South Korea.
Abstract
OBJECTIVE: To evaluate the value of the gadobenate dimeglumine-enhanced hepatobiliary-phase magnetic resonance (MR) imaging for the differentiation of scirrhous hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) with or without HCC. MATERIALS AND METHODS: We retrospectively evaluated unenhanced and gadobenate dimeglumine-enhanced dynamic and hepatobiliary-phase MR images of five patients with scirrhous HCCs and 29 patients with 57 CCs with or without HCC with statistical analysis using Fisher's exact test. RESULTS: Peripheral hyperintensity compared with the center on T2-weighted images was more frequent for scirrhous HCCs (n = 3, 60%) as compared to CCs with or without HCC (n = 7, 12%) (P = 0.026). There was no significant difference in the gadobenate dimeglumine-enhanced dynamic imaging of both scirrhous HCC and CC with or without HCC (P > 0.05). On hepatobiliary-phase images, scirrhous HCC showed no target appearance as compared with that 50 (87.7%) CCs with or without HCC showed target appearance (P < 0.001). CONCLUSION: Although both scirrhous HCC and CC with or without HCC show similar imaging findings on unenhanced and gadobenate dimeglumine-enhanced dynamic MR images, gadobenate dimeglumine-enhanced hepatobiliary-phase MR images may be helpful to differentiate scirrhous HCC from CC with or without HCC.
OBJECTIVE: To evaluate the value of the gadobenate dimeglumine-enhanced hepatobiliary-phase magnetic resonance (MR) imaging for the differentiation of scirrhous hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) with or without HCC. MATERIALS AND METHODS: We retrospectively evaluated unenhanced and gadobenate dimeglumine-enhanced dynamic and hepatobiliary-phase MR images of five patients with scirrhous HCCs and 29 patients with 57 CCs with or without HCC with statistical analysis using Fisher's exact test. RESULTS: Peripheral hyperintensity compared with the center on T2-weighted images was more frequent for scirrhous HCCs (n = 3, 60%) as compared to CCs with or without HCC (n = 7, 12%) (P = 0.026). There was no significant difference in the gadobenate dimeglumine-enhanced dynamic imaging of both scirrhous HCC and CC with or without HCC (P > 0.05). On hepatobiliary-phase images, scirrhous HCC showed no target appearance as compared with that 50 (87.7%) CCs with or without HCC showed target appearance (P < 0.001). CONCLUSION: Although both scirrhous HCC and CC with or without HCC show similar imaging findings on unenhanced and gadobenate dimeglumine-enhanced dynamic MR images, gadobenate dimeglumine-enhanced hepatobiliary-phase MR images may be helpful to differentiate scirrhous HCC from CC with or without HCC.
Authors: Anastasia Murtha-Lemekhova; Juri Fuchs; Erik Schulz; Anthe Suzan Sterkenburg; Philipp Mayer; Jan Pfeiffenberger; Katrin Hoffmann Journal: J Hepatocell Carcinoma Date: 2021-10-22