OBJECTIVE: To present a case of culture-proven typhoid fever in which granulomas were demonstrated histologically in the ileum and mesenteric lymph nodes. CLINICAL PRESENTATION AND INTERVENTION: A 47-year-old Pakistani man underwent emergency hemicolectomy for severe bleeding per rectum associated with diarrhea. Two large ulcers in the ileum, near the ileocolic junction, as well as mesenteric lymph nodes showed both necrotizing and non-necrotizing granulomas in addition to mixed inflammatory infiltrate on histology. CONCLUSION: Typhoid fever may be considered as one of the causes of the differential diagnoses of granulomatous inflammation of the small intestine. Copyright 2009 S. Karger AG, Basel.
OBJECTIVE: To present a case of culture-proven typhoid fever in which granulomas were demonstrated histologically in the ileum and mesenteric lymph nodes. CLINICAL PRESENTATION AND INTERVENTION: A 47-year-old Pakistani man underwent emergency hemicolectomy for severe bleeding per rectum associated with diarrhea. Two large ulcers in the ileum, near the ileocolic junction, as well as mesenteric lymph nodes showed both necrotizing and non-necrotizing granulomas in addition to mixed inflammatory infiltrate on histology. CONCLUSION:Typhoid fever may be considered as one of the causes of the differential diagnoses of granulomatous inflammation of the small intestine. Copyright 2009 S. Karger AG, Basel.
Authors: Stephen J Libby; Michael A Brehm; Dale L Greiner; Leonard D Shultz; Michael McClelland; Kelly D Smith; Brad T Cookson; Joyce E Karlinsey; Traci L Kinkel; Steffen Porwollik; Rocio Canals; Lisa A Cummings; Ferric C Fang Journal: Proc Natl Acad Sci U S A Date: 2010-08-16 Impact factor: 11.205
Authors: Julie A Bettke; Jason W Tam; Valeria Montoya; Brian P Butler; Adrianus W M van der Velden Journal: Infect Immun Date: 2022-03-21 Impact factor: 3.609