Ron H J Mathijssen, Howard Gurney. Show Affiliations »
Abstract
Mesh： See more » Antineoplastic Agents, Phytogenic/administration & dosageAntineoplastic Agents, Phytogenic/adverse effectsAntineoplastic Agents, Phytogenic/pharmacokineticsBiotransformation/geneticsCamptothecin/administration & dosageCamptothecin/adverse effectsCamptothecin/analogs & derivativesCamptothecin/pharmacokineticsColorectal Neoplasms/drug therapyColorectal Neoplasms/geneticsColorectal Neoplasms/metabolismDrug Administration ScheduleGenetic Predisposition to DiseaseGlucuronosyltransferase/geneticsGlucuronosyltransferase/metabolismHepatocyte Nuclear Factor 1-alpha/geneticsHumansIrinotecanLiver-Specific Organic Anion Transporter 1Multidrug Resistance-Associated Proteins/geneticsMultidrug Resistance-Associated Proteins/metabolismNeutropenia/chemically inducedNeutropenia/geneticsOrganic Anion Transporters/geneticsOrganic Anion Transporters/metabolismPatient SelectionPhenotypePolymorphism, GeneticRisk AssessmentRisk FactorsTreatment Outcome
Substances： See more » Antineoplastic Agents, PhytogenicHNF1A protein, humanHepatocyte Nuclear Factor 1-alphaLiver-Specific Organic Anion Transporter 1Multidrug Resistance-Associated ProteinsOrganic Anion TransportersSLCO1B1 protein, humanmultidrug resistance-associated protein 2IrinotecanUGT1A1 enzymeGlucuronosyltransferaseCamptothecinmultidrug resistance-associated protein 1
Year: 2009 PMID： 19349537 DOI： 10.1200/JCO.2008.21.2480
Source DB: PubMed Journal: J Clin Oncol ISSN： 0732-183X Impact factor: 44.544