Loss of pyrrolizidine alkaloids on decomposition of ragwort (Senecio jacobaea) as measured by LC-TOF-MS.

The decomposition of toxic pyrrolizidine alkaloids in ragwort (Senecio jacobaea) on storage in waste bags has been evaluated by a new time-of-flight mass spectrometric detection method. The method makes progress in meeting the clear need for modern analytical methods for pyrrolizidine alkaloids and for studies into factors affecting the stability of the toxins in the uprooted plant, which might still be accessible to animals. The experiments demonstrated a rapid decomposition of the toxins in ragwort stored in bags, from 340 mg/kg to less than 40 mg/kg in four weeks and virtually complete loss after 10 weeks. The information obtained can guide effective ragwort removal procedures to safeguard grazing animals.