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Literature DB >> 19348032

Specificity concerns with antibodies for receptor mapping.

Peter Kirkpatrick.

Abstract

Mesh：

Substances：

Year: 2009 PMID： 19348032 DOI： 10.1038/nrd2854

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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7 in total

1. Should we be cautious on the use of commercially available antibodies to dopamine receptors?

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2. Lack of specificity of commercially available antisera against muscarinergic and adrenergic receptors.

Authors: Wisuit Pradidarcheep; Jan Stallen; Wil T Labruyère; Noshir F Dabhoiwala; Martin C Michel; Wouter H Lamers
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2009-02-07 Impact factor: 3.000

3. Ten commercial antibodies for alpha-1-adrenergic receptor subtypes are nonspecific.

Authors: Brian C Jensen; Philip M Swigart; Paul C Simpson
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2008-11-07 Impact factor: 3.000

4. Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice.

Authors: Gitte Jositsch; Tamara Papadakis; Rainer V Haberberger; Miriam Wolff; Jürgen Wess; Wolfgang Kummer
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2008-10-31 Impact factor: 3.000

5. Lack of specificity of antibodies directed against human beta-adrenergic receptors.

Authors: Nazha Hamdani; Jolanda van der Velden
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2009-01-22 Impact factor: 3.000

6. Where is TRPV1 expressed in the bladder, do we see the real channel?

Authors: Wouter Everaerts; M Rosario Sepúlveda; Thomas Gevaert; Tania Roskams; Bernd Nilius; Dirk De Ridder
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2009-01-20 Impact factor: 3.000

7. Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice.

Authors: Xiaoying Lu; Tamas Bartfai
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2009-01-22 Impact factor: 3.000

7 in total

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Review 1. Therapeutic antibodies directed at G protein-coupled receptors.

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Authors: Shaun Sandow; T Hilton Grayson
Journal: Br J Pharmacol Date: 2011-07 Impact factor: 8.739

3. Editorial: Antibody can get it right: confronting problems of antibody specificity and irreproducibility.

Authors: Agnes Schonbrunn
Journal: Mol Endocrinol Date: 2014-09

4. A putative role for platelet-derived PPARγ in vascular homeostasis demonstrated by anti-PPARγ induction of bleeding, thrombocytopenia and compensatory megakaryocytopoiesis.

Authors: Patricia J Simpson-Haidaris; Kathryn E Seweryniak; Sherry L Spinelli; Tatiana M Garcia-Bates; Thomas I Murant; Stephen J Pollock; Patricia J Sime; Richard P Phipps
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Review 5. Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry.

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