Literature DB >> 1934745

Ultrastructural differences between the cells of the medical collateral and the anterior cruciate ligaments.

R M Lyon1, W H Akeson, D Amiel, L R Kitabayashi, S L Woo.   

Abstract

The anterior cruciate ligament (ACL) does not heal after an interstitial tear, in contrast to the medial collateral ligament (MCL), whose interstitial tears heal readily. The light microscopic and ultrastructural differences between the cells of the two ligaments were studied in rabbit knees to observe the healing characteristics of the two ligaments. A rabbit knee was chosen because the rabbit ACL, like that of humans, does not heal following interstitial injury. The cells populating the MCL have the characteristics of fibroblasts. The cells of the ACL resemble fibrocartilage cells. The phenotypic differences in the cells of the two ligaments may be important determinants of the differences in healing.

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Year:  1991        PMID： 1934745

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN： 0009-921X            Impact factor:   4.176


  16 in total

1.  Collagen fibril diameter distributions in rabbit anterior cruciate and medial collateral ligaments: changes with maturation.

Authors:  R A Hart; W H Akeson; K Spratt; D Amiel
Journal:  Iowa Orthop J       Date:  1999

2.  Fetal ACL fibroblasts exhibit enhanced cellular properties compared with adults.

Authors:  Simone S Stalling; Steven B Nicoll
Journal:  Clin Orthop Relat Res       Date:  2008-07-22       Impact factor: 4.176

3.  Decrease in fibronectin occurs coincident with the increased expression of its integrin receptor alpha5beta1 in stress-deprived ligaments.

Authors:  S S AbiEzzi; R A Foulk; F L Harwood; W H Akeson; D Amiel
Journal:  Iowa Orthop J       Date:  1997

4.  The effects of immobilization on the maturation of the anterior cruciate ligament of the rabbit knee.

Authors:  D Amiel; C D Wallace; F L Harwood
Journal:  Iowa Orthop J       Date:  1994

5.  TIEG1-null tenocytes display age-dependent differences in their gene expression, adhesion, spreading and proliferation properties.

Authors:  Oualid Haddad; Laurie Gumez; John R Hawse; Malayannan Subramaniam; Thomas C Spelsberg; Sabine F Bensamoun
Journal:  Exp Cell Res       Date:  2011-05-18       Impact factor: 3.905

6.  Platelets and plasma proteins are both required to stimulate collagen gene expression by anterior cruciate ligament cells in three-dimensional culture.

Authors:  Mingyu Cheng; Hao Wang; Ryu Yoshida; Martha Meaney Murray
Journal:  Tissue Eng Part A       Date:  2010-05       Impact factor: 3.845

7.  The differential adhesion forces of anterior cruciate and medial collateral ligament fibroblasts: effects of tropomodulin, talin, vinculin, and alpha-actinin.

Authors:  K L Sung; L Yang; D E Whittemore; Y Shi; G Jin; A H Hsieh; W H Akeson; L A Sung
Journal:  Proc Natl Acad Sci U S A       Date:  1996-08-20       Impact factor: 11.205

Review 8.  Current status and potential of primary ACL repair.

Authors:  Martha M Murray
Journal:  Clin Sports Med       Date:  2009-01       Impact factor: 2.182

9.  Age-related changes in human PCLs: a light and electron microscopic study.

Authors:  Mustafa F Sargon; M Nedim Doral; O Ahmet Atay
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2003-10-29       Impact factor: 4.342

10.  New era in health care: tissue engineering.

Authors:  S Parveen; K Krishnakumar; Sk Sahoo
Journal:  J Stem Cells Regen Med       Date:  2006-12-26
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