OBJECTIVE: To assess patient outcome and imaging findings of patients with pulmonary embolism of fluid silicone. METHODS: Medical records and imaging examinations of 10 patients with respiratory distress after illicit injection of fluid silicone were reviewed. Population consisted of 8 male (6 male-to-female transsexuals) and 2 female subjects. RESULTS: Average age was 29 years. Most common injection sites were gluteal and trochanteric. Respiratory symptoms developed between 15 minutes and 2 days after silicone injection. Five referred fever, 6 developed adult respiratory distress syndrome, and 2 subsequently died. Alveolar hemorrhage was demonstrated on pathological examination in 6, with silicone vacuoles in the lung parenchyma in 3. Computed tomography demonstrated peripheral ground glass opacities with interlobular septal thickening in all and peripheral airspace disease in 7. CONCLUSIONS: Illicit injection of large volumes of fluid silicone for cosmetic purposes is associated with pulmonary embolism and acute alveolar hemorrhage and is associated with a significant mortality.
OBJECTIVE: To assess patient outcome and imaging findings of patients with pulmonary embolism of fluid silicone. METHODS: Medical records and imaging examinations of 10 patients with respiratory distress after illicit injection of fluid silicone were reviewed. Population consisted of 8 male (6 male-to-female transsexuals) and 2 female subjects. RESULTS: Average age was 29 years. Most common injection sites were gluteal and trochanteric. Respiratory symptoms developed between 15 minutes and 2 days after silicone injection. Five referred fever, 6 developed adult respiratory distress syndrome, and 2 subsequently died. Alveolar hemorrhage was demonstrated on pathological examination in 6, with silicone vacuoles in the lung parenchyma in 3. Computed tomography demonstrated peripheral ground glass opacities with interlobular septal thickening in all and peripheral airspace disease in 7. CONCLUSIONS: Illicit injection of large volumes of fluid silicone for cosmetic purposes is associated with pulmonary embolism and acute alveolar hemorrhage and is associated with a significant mortality.
Authors: Ronaldo Ferreira Macedo; Ricardo Ananias Lobão; Eduardo Mello de Capitani; Maira Eliza Petrucci Zanovello; Paula Catarina Caruso; Maurício Souza de Toledo Leme; Elza Maria Figueiras Pedreira de Cerqueira; Lair Zambon Journal: J Bras Pneumol Date: 2013 May-Jun Impact factor: 2.624
Authors: Kirill Lyapichev; Felix Manuel Chinea; Julio Poveda; Jeniffer Pereda; Pablo A Bejarano; Monica T Garcia-Buitrago Journal: Case Rep Pathol Date: 2016-01-27
Authors: S Bryn Austin; Allegra R Gordon; Grace A Kennedy; Kendrin R Sonneville; Jeffrey Blossom; Emily A Blood Journal: Int J Environ Res Public Health Date: 2013-12-06 Impact factor: 3.390